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2018-06-12 at 11:03 PM UTC
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Everyone's favorite porn!?!?!?
fisting nuns ftw
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2018-09-04 at 3:09 AM UTC
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Trump in deep shit now
Originally posted by infinityshock
niggers dont think. theyre not capable of such advanced evolutionary techniques
and you call what you do thinking? lolol
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sasha grey is my spirit animal
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Interesting
https://www.newscientist.com/article/2178001-opioid-crisis-powerful-but-non-addictive-drug-could-replace-morphine/A new opioid drug blocks pain in monkeys without any apparent addictive or dangerous side-effects.
Opioids like morphine, oxycodone and fentanyl are good at stopping pain but can also be addictive. In the US alone, more than 46 people die every day from overdoses involving prescription opioids.
Mei-Chuan Ko at Wake Forest University in the US and his colleagues found they could simultaneously block pain and prevent addiction using a drug that activates two types of opioid receptors in the brain.
The first receptor – the mu opioid receptor – is the classic pain-relieving receptor targeted by traditional opioids. The second – the nociceptin opioid receptor – blocks the brain’s addiction-forming response, while also providing additional pain relief.
The drug, named AT-121, was 100 times better at reducing pain in monkeys than morphine. Ko and his colleagues assessed this by measuring how long the animals were prepared to keep their tails in uncomfortably warm water at 50°C after taking varying doses of the two drugs.
Stopping addiction
The novel opioid also had no apparent addictive properties. The monkeys in the study readily self-administered oxycodone and cocaine but not AT-121. This is a promising finding because monkeys and humans are close evolutionary relations and have similar addiction mechanisms, says Ko.
Another advantage was that AT-121 didn’t cause breathing problems, even at high doses. Existing opioids are dangerous when taken in excess because they can interfere with people’s ability to breathe.
At the moment, the drug must be administered by injection, but Ko’s team is working on developing a pill form.
The researchers hope to begin a clinical trial of AT-121 in 18 months’ time. If successful, it could become available to consumers in the next 6 years.
Journal reference: Science Translational Medicine, DOI: 10.1126/scitranslmed.aar3483
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Originally posted by RisiR †
Do you still have the tab open? Can you copy the link?
yeah but when you copy/pasta it just opens up the site that uses the plugin tho.
https://thetruesize.com/#?borders=1~!MTcwMjAzNzQ.MjE1MjU1OQ*MzYwMDAwMDA(MA
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Originally posted by infinityshock
youd have a whole different attitude if you knew the fapping fantasies i go through when im fapping to thoughts of you
why would i give a shit? you don't exist in my reality so it doesn't affect me in the slightest. you're just fiction to me you fool.
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2018-08-30 at 5:08 PM UTC
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Sexual Preference Discussion
Originally posted by MORALLY SUPERIOR BEING 2.0 - The GMO Reckoning
And pee
pee from a woman tho.
i honestly do not understand how the fuck anybody can be turned on by a cock tbph. not even women, altho obvs i'm glad that women are turned on by them, but i still don't get it tho. i mean what the fuck is so attractive about them anyway? they look like fucking nasty awful things.
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2018-08-30 at 1:58 PM UTC
in
cat within a cat
thought this was kinda cool, thought i'd share.
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Originally posted by Speedy Parker
Stop whining snowflake
he does have a pretty funny username tho.
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Media fear mongering and brainwashing. Drug users and dealers do make a perfect enemy that control freaks can use to offer security and protection from. The very idea that peoples kids are in grave danger from drugs does scare the living shit out of parents. Once they've been scared shirtless they will do anything and become totally subservient to any "authority" that convince them they can offer them some kind of security from the perceived peril.
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Originally posted by ~L J~
No clue who that is, so nope lol.
it was just i banged this chick called jen on monday too so wondered if by any chance you were her.
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Originally posted by DietPiano
Went to one of those yuppie clothing stores today. AE and Buckle.
Salesbro -he was bro- came up to me and made me let him help me, I kind of brushed him off saying like "Any sales going on?" "Not really? "Okay sounds good." but he came back to me after like five minutes, more persistent this time.
He starts asking me personal questions- What I do, where I go to school, where I'm from. I know what he's doing but entertain him and stop him after a while and tell him that I want long sleeve shirts. It was actually nice though, becus he was able to find some 3/4 sleeve tees, which I think will look a lot better than full sleeves in warm weather.
He starts asking me why I want them, which I think is a weird question to ask someone. Do you really expect to get a wholesome answer here?
Anyway, I lie and tell him I have Psoriasis, and he says "Oh, yah, my Dah has thaat, do yah have any joint issues tuue? Where is it? Do you take Humira? No? Why not, don't you have insurance?" It didn't really bother me that much, he was a decent guy who was just curious.. but that's getting pretty personal.
Anyway, he found a lot of good stuff though. It is kind of nice having a salesperson pick stuff out for you when you don't know what you want.
i hate nosey cunts like that. i would have literally told him to fuck off and mind his own business.
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Originally posted by stupid noob
You're still an ugly faggot.
yeah but you love ugly so much you married it.
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Originally posted by Rock_N_Rollover
You keep mentioning feed their habit. Means they're addicted.
And you want it legalized?
It would be nice to know how many more people would become addicted because it became legal.
those people who would use heroin if it was legal but don't because it is not are most likely using alcohol now which is a worse drug, a much more damaging substance. they would be better off using heroin.
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2018-08-13 at 10:04 AM UTC
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Are you afraid to die?
Originally posted by infinityshock
if you want to see the value of pussy, pick the hottest pussy that gives you the most raging boner of all time…
then take androgen antagonists for a few weeks
then go look at the hot pussy again and see how arousing it is to you.
I think I'll pass thx. I already know the value of pussy, about £100 an hour.
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2018-08-12 at 8:25 PM UTC
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Are you afraid to die?
Originally posted by EllariaSand
Since I’m certain we don’t “end” after death….I strongly believe we didn’t “begin” at birth….or this birth
I would stake my life on it since after the experience I had I am 100% certain we continue to exist as “ourselves” after we pass from this life
As for not remembering what was before we were born….maybe we do, but given we’re babies and can’t talk….by the time we can talk we don’t have the vocabulary to properly express our pre birth memories….or they’re dismissed as a child’s imagination?
Or perhaps when we pass this exsistance is forgotten
I don’t know how exactly it works but I know it’s true
people who believe in existence after death are just scared to die. they won't allow themselves to accept the fact that one day they won't exist in any form.
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Originally posted by Technologist
Narc,
Even though I feel heroin is a nasty drug for MOST, you seek to be somewhat of a functioning user. I can’t say for sure, I don’t really know you, but you seem to be an intelligent man. If it rules your every waking moment, that’s a problem.
Now you can talk about your use in a positive light, but for the majority, heroin ruins people’s lives. I don’t know about England, but the US is suffering a major crisis. The rural areas in Ohio are getting eaten with heroin users. So many sad deaths.
its prohibition that makes it such a problem. its because of prohibition that nobody knows the purity of their supply from one bag to the next. you can't judge your dose properly when you don't know the purity and this is why people accidentally overdose. because of prohibition people hide away to use where nobody will find them if they overdose. and prohibition pushes up the prices so users have to resort to theft and often violence in order to fund the habit. prohibition means suppliers cannot sort their disputes through the usual legal processes and so end up resorting to violence as the only solution open to them. without prohibition all those problems would go away. there would be much less risk of you being violently robbed by a desperate addict and everybodies insurance premiums would go right down. why anybody is in favor of prohibition which is so damaging to society is beyond me.
also just think of all the money saved by the authorities trying to fight the drug problem, less tax dollars spent on law enforcement, prisons, courts and legal costs. all that money could be put to much better use making your community a much nicer richer place to live.
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this is what the media do with drugs, they take the very worst isolated case they can find then report it like that is common place with the drug. they always conveniently forget to mention any other factors that are/were involved also.
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Originally posted by LegalizeSpiritualDiscovery
At least I'm not a bathtub.
No I see you as more of a bathroom sink kinda guy.
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