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Posts by stl1
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2021-10-14 at 6:56 PM UTC in Worldwide Protests Over Vaccine MandatesResistance is futile.
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2021-10-14 at 6:50 PM UTC in Would you let a woman work on your car?You're
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2021-10-14 at 6:44 PM UTC in what's the last thing you bought?Sam's Club yesterday and bought a bag of 18 count petite white hoagie rolls, 2 tubs of chicken salad and a tub of potato salad.
Quick and easy meals with no cooking. I freeze the rolls before they get too old. I cut them in half lengthwise and hollow out the top portion and then fill it with the chicken salad. Good stuff. -
2021-10-14 at 6:38 PM UTC in Would you let a woman work on your car?No, but Lisa was good people and an excellent service person. She had outstanding electrical troubleshooting skills.
The last time I saw her was when I was having lunch at a McDonalds while working for another company and she gave me a big hug and made sure to introduce me to the tech she was riding with. -
2021-10-14 at 6:29 PM UTC in What's the deal with Strip Club Private Rooms?
Originally posted by ⠀⠀⠀⠀⠀⠀ "Ma'am… what exactly do I get with this ten dollars?"
I remember being barely legal at a strip joint over in East St. Louis as a kid with some buddies and they put quarters on the stage. Pissed that dancer off! She kicked the quarters off the stage, security came over and we came real close to getting kicked out of the joint. Good times! -
2021-10-14 at 5:30 PM UTC in Would you let a woman work on your car?I used to work at a shop with a lesbian HVAC service tech. When I was out with a broken collarbone and unable to work, my sister called me because her A/C wasn't working. I advised her to call my employer and ask that Lisa be sent out for the repair rather than one of the other techs.
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2021-10-14 at 5:23 PM UTC in $1,000 for details on a certain gentlemanlol
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2021-10-14 at 5:21 PM UTC in Would you let a woman work on your car?I took a buddy out to the booniess to pick his car up after his mechanic had worked on it. The mechanic had a very masculine face and long hair and titties.
God damn freak show. -
2021-10-14 at 5:16 PM UTC in What if a nigger raped and killed your mom before your eyes?I was not talking to you.
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2021-10-14 at 5:10 PM UTC in What if a nigger raped and killed your mom before your eyes?What do you charge to fulfill this fantasy?
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2021-10-14 at 5:05 PM UTC in 486 Will it start today?What I want to know is if Jiggly Booty has offered any assistance to get this 486 pos up and running?
I mean, he claims to be so good at this stuff and all...
Why ain't it up and running yet? -
2021-10-14 at 4:57 PM UTC in POWERING ON MY $600 486 GAMING COMPUTER!
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2021-10-14 at 4:51 PM UTC in POWERING ON MY $600 486 GAMING COMPUTER!
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2021-10-14 at 4:47 PM UTC in $1,000 for details on a certain gentleman
Originally posted by Incessant You’re an idiot and a weirdo OP. I don’t know who Jake is, but I’m not him. And I’m not from DH. Apparently ignoring your PMs didn’t do enough so I’ll just say it here.
I’m not Jake, I don’t know who Jake is, and in case anyone’s wants to know who Larry is looking for I’m assuming it’s Jake.
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2021-10-14 at 4:27 PM UTC in I Like Turtles2-Headed Baby Turtle Thrives at Massachusetts Animal Refuge
A rare two-headed diamondback terrapin turtle is alive and kicking — with all six of its legs — at the Birdsey Cape Wildlife Center in Massachusetts after hatching two weeks ago.
Associated Press
BARNSTABLE, Mass. (AP) — A rare two-headed diamondback terrapin turtle is alive and kicking — with all six of its legs — at the Birdsey Cape Wildlife Center in Massachusetts after hatching two weeks ago.
A threatened species in the state, this turtle is feeding well on blood worms and food pellets, staff at the center say. The two heads operate independently, coming up for air at different times, and inside its shell are two gastrointestinal systems to feed both sides of its body.
The turtle originally came from a nest in West Barnstable that researchers determined was in a hazardous location and needed to be moved. After hatching, turtles in these so-called “head start” nests are sent to different care centers to be monitored before their release in the spring, The Cape Cod Times reported.
Center veterinarian Pria Patel and other staff members will continue to monitor the turtle, which they nicknamed Mary-Kate and Ashley Olsen after the twin child stars. The staff is hoping to perform a CT scan to learn more about its circulatory system.
https://www.snopes.com/ap/2021/10/13/2-headed-baby-turtle-thrives-at-massachusetts-animal-refuge/?utm_campaign=Snopes%20Debunker%20-%20Wednesday%2C%20October%2013%2C%202021%20-%20Tonight%3A%20Delta%20pilot%20death%20rumors%2C%20vaccines%20and%20human%20blood%20color%2C%20a%20Southwest%20rumor%2C%20and%20fast%20food%20labor%20shortages%20%28UEKzmj%29&utm_medium=email&utm_source=Snopes%20Debunker%20-%20Wednesday%20Edition -
2021-10-14 at 4:04 PM UTC in THE MAGA PARTY!,,, the GOP is dead, republicans are going down with the dems,, get ready for THE MAGA PARTY lefty'sReuters
Anti-Trump Republicans to back vulnerable Democratic lawmakers in 2022 congressional races
By Tim Reid
LOS ANGELES (Reuters) - A group of anti-Trump Republicans on Thursday will endorse a slate of Democratic lawmakers facing tough races in next year's midterm elections, in a bid to stop the Republican Party from retaking control of Congress.
The officials, dismayed that most elected Republicans now embrace former President Donald Trump's false claims that the 2020 election was stolen, told Reuters they are also backing vulnerable Republicans, including Representative Liz Cheney, who have rejected Trump's voter fraud allegations.
The Renew America Movement (RAM), formed by centrist Republicans after a mob of Trump supporters stormed Congress on Jan. 6 to try to stop lawmakers from certifying Democratic President Joe Biden's election victory, concedes that Trump and his conspiracy theories now have an iron grip on the party.
According to a Reuters/Ipsos poll from August, 30% of U.S. adults agreed that the "2020 election was stolen from Donald Trump." That included 61% of Republicans, 19% of independents and 10% of Democrats.
Trump, for his part, has endorsed several candidates mounting primary challenges to Republican lawmakers who voted to impeach him on a charge of inciting insurrection in a fiery speech ahead of the deadly Jan. 6 assault on the Capitol.
He has also backed a challenger to Republican Senator Lisa Murkowski of Alaska, one of seven in her party who voted to convict Trump on the charge. He was ultimately acquitted by the Senate.
RAM, whose leadership includes former Republican Governors Christine Todd Whitman of New Jersey and Bill Weld of Massachusetts, said supporting moderate candidates is vital to safeguarding American democracy.
"With the mounting threats to our democracy and Constitution, we need people who work proactively to lead their party and the country away from the political extremes," Joel Searby, the group's national political director, told Reuters.
RAM will endorse and in many cases campaign for 11 moderate Democrats, nine moderate Republicans and one independent running for the House of Representatives and Senate in the November 2022 elections, the officials said.
Democrats have a narrow majority in the House, while the Senate is tied 50-50. Party insiders are increasingly nervous about losing both chambers next year, which would derail Biden's agenda.
The lawmakers to be backed by RAM include Representative Abigail Spanberger of Virginia and Elissa Slotkin of Michigan, and Senator Mark Kelly of Arizona, all Democrats locked in close contests.
The group is also supporting Republican House members such as Cheney of Wyoming and Adam Kinzinger from Illinois, who are among a handful of elected Republicans to denounce Trump and his baseless voter fraud claims. Trump's allegations were rejected by dozens of courts, state election officials and members of his own administration. -
2021-10-14 at 3:56 PM UTC in STICK IT, Damn It!The New York Times
Newly Discovered Bat Viruses Give Hints to Covid’s Origins
Carl Zimmer
In the summer of 2020, half a year into the coronavirus pandemic, scientists traveled into the forests of northern Laos to catch bats that might harbor close cousins of the pathogen.
In the dead of night, they used mist nets and canvas traps to snag the animals as they emerged from nearby caves, gathered samples of saliva, urine and feces, then released them back into the darkness.
The fecal samples turned out to contain coronaviruses, which the scientists studied in high security biosafety labs, known as BSL-3, using specialized protective gear and air enhancements.
Three of the Laos coronaviruses were unusual: They carried a molecular hook on their surface that was very similar to the hook on the virus that causes Covid-19, called SARS-CoV-2. Like SARS-CoV-2, their hook allowed them to latch onto human cells.
“It is even better than early strains of SARS-CoV-2,” said Marc Eloit, a virologist at the Pasteur Institute in Paris who led the study, referring to how well the hook on the Laos coronaviruses binds to human cells. The study was posted online last month and has not yet been published in a scientific journal.
Virus experts are buzzing about the discovery. Some suspect that these SARS-CoV-2-like viruses may already be infecting people from time to time, causing only mild and limited outbreaks. But under the right circumstances, the pathogens could give rise to a Covid-19-like pandemic, they say.
The findings also have significant implications for the charged debate over Covid’s origins, experts say. Some people have speculated that SARS-CoV-2’s impressive ability to infect human cells could not have evolved through a natural spillover from an animal. But the new findings seem to suggest otherwise.
“That really puts to bed any notion that this virus had to have been concocted, or somehow manipulated in a lab, to be so good at infecting humans,” said Michael Worobey, a University of Arizona virologist who was not involved in the work.
These bat viruses, along with more than a dozen others discovered in recent months in Laos, Cambodia, China and Thailand, may also help researchers better anticipate future pandemics. The viruses’ family trees offer hints about where potentially dangerous strains are lurking, and which animals scientists should look at to find them.
Last week, the U.S. government announced a $125 million project to identify thousands of wild viruses in Asia, Latin America and Africa to determine their risk of spillover. Dr. Eloit predicted that there were many more relatives of SARS-CoV-2 left to find.
“I am a fly fisherman,” he said. “When I am unable to catch a trout, that doesn’t mean there are no trout in the river.”
When SARS-CoV-2 first came to light, its closest known relative was a bat coronavirus that Chinese researchers found in 2016 in a mine in southern China’s Yunnan Province. RaTG13, as it is known, shares 96 percent of its genome with SARS-CoV-2. Based on the mutations carried by each virus, scientists have estimated that RaTG13 and SARS-CoV-2 share a common ancestor that infected bats about 40 years ago.
Both viruses infect cells by using a molecular hook, called the “receptor-binding domain,” to latch on to their surface. RaTG13’s hook, adapted for attaching to bat cells, can only cling weakly to human cells. SARS-CoV-2’s hook, by contrast, can clasp cells in the human airway, the first step toward a potentially lethal case of Covid-19.
To find other close relatives of SARS-CoV-2, wildlife virus experts checked their freezers full of old samples from across the world. They identified several similar coronaviruses from southern China, Cambodia, and Thailand. Most came from bats, while a few came from scaly mammals known as pangolins. None was a closer relative than RaTG13.
Dr. Eloit and his colleagues instead set out to find new coronaviruses.
They traveled to northern Laos, about 150 miles from the mine where Chinese researchers had found RaTG13. Over six months they caught 645 bats, belonging to 45 different species. The bats harbored two dozen kinds of coronaviruses, three of which were strikingly similar to SARS-CoV-2 — especially in the receptor-binding domain.
In RaTG13, 11 of the 17 key building blocks of the domain are identical to those of SARS-CoV-2. But in the three viruses from Laos, as many as 16 were identical — the closest match to date.
Dr. Eloit speculated that one or more of the coronaviruses might be able to infect humans and cause mild disease. In a separate study, he and colleagues took blood samples from people in Laos who collect bat guano for a living. Although the Laotians did not show signs of having been infected with SARS-CoV-2, they carried immune markers, called antibodies, that appeared to be caused by a similar virus.
Linfa Wang, a molecular virologist at the Duke-NUS Medical School in Singapore who was not involved in the study, agreed that such an infection was possible, since the newly discovered viruses can attach tightly to a protein on human cells called ACE2.
“If the receptor binding domain is ready to use ACE2, these guys are dangerous,” Dr. Wang said.
Paradoxically, some other genes in the three Laotian viruses are more distantly related to SARS-CoV-2 than other bat viruses. The cause of this genetic patchwork is the complex evolution of coronaviruses.
If a bat infected with one coronaviruses catches a second one, the two different viruses may end up in a single cell at once. As that cell begins to replicate each of those viruses, their genes get shuffled together, producing new virus hybrids.
In the Laotian coronaviruses, this gene shuffling has given them a receptor-binding domain that’s very similar to that of SARS-CoV-2. The original genetic swap took place about a decade ago, according to a preliminary analysis by Spyros Lytras, a graduate student at the University of Glasgow in Scotland.
Mr. Lytras and his colleagues are now comparing SARS-CoV-2 not just to the new viruses from Laos, but to other close relatives that have been found in recent months. They’re finding even more evidence of gene shuffling. This process — known as recombination — may be reshaping the viruses from year to year.
“It’s becoming more and more obvious how important recombination is,” Mr. Lytras said.
He and his colleagues are now drawing the messy evolutionary trees of SARS-CoV-2-like viruses based on these new insights. Finding more viruses could help clear up the picture. But scientists are divided as to where to look for them.
Dr. Eloit believes the best bet is a zone of Southeast Asia that includes the site where his colleagues found their coronaviruses, as well as the nearby mine in Yunnan where RaTG13 was found.
“I think the main landscape corresponds to north Vietnam, north Laos and south China,” Dr. Eloit said.
The U.S. government’s new virus-hunting project, called DEEP VZN, may turn up one or more SARS-CoV-2-like viruses in that region. A spokesman for USAID, the agency funding the effort, named Vietnam as one of the countries where researchers will be searching, and said that new coronaviruses are one of their top priorities.
Other scientists think it’s worth looking for relatives of SARS-CoV-2 further afield. Dr. Worobey of the University of Arizona said that some bat coronaviruses carrying SARS-CoV-2-like segments have been found in eastern China and Thailand.
“Clearly the recombination is showing us that these viruses are part of a single gene pool over hundreds and hundreds of miles, if not thousands of miles,” Dr. Worobey said.
Colin Carlson, a biologist at Georgetown University, suspects that a virus capable of producing a Covid-like outbreak might be lurking even further away. Bats as far east as Indonesia and as far west as India, he noted, share many biological features with the animals known to carry SARS-CoV-2-like viruses.
“This is not just a Southeast Asia problem,” Dr. Carlson said. “These viruses are diverse, and they are more cosmopolitan than we have thought.”
The interest in the origins of the pandemic has put renewed attention on the safety measures researchers are using when studying potentially dangerous viruses. To win DEEP VZN grants, scientists will have to provide a biosafety and biosecurity plan, according to a USAID spokesman, including training for staff, guidelines on protective equipment to be worn in the field and safety measures for lab work.
If scientists find more close cousins of SARS-CoV-2, it doesn’t necessarily mean they pose a deadly threat. They might fail to spread in humans or, as some scientists speculate, cause only small outbreaks. Just seven coronaviruses are known to have jumped the species barrier to become well-established human pathogens.
“There’s probably a vast range of other coronaviruses that end up going nowhere,” said Jessica Metcalf, an evolutionary ecologist at Princeton University.
Still, recombination may be able to turn a virus going nowhere into a new threat. In May, researchers reported that two coronaviruses in dogs recombined in Indonesia. The result was a hybrid that infected eight children.
“When a coronavirus that we have monitored for decades, that we think of as just something our pets can get, can make the jump — we should have seen that coming, right?” Dr. Carlson said. -
2021-10-13 at 9:28 PM UTC in how come you get muscle pains in yourHow old are you and when did you get your Covid 2nd jab?
CDC
COVID-19 Vaccination
Clinical Care
Clinical Considerations: Myocarditis and Pericarditis after Receipt of mRNA COVID-19 Vaccines Among Adolescents and Young Adults
Summary
Since April 2021, increased cases of myocarditis and pericarditis have been reported in the United States after mRNA COVID-19 vaccination (Pfizer-BioNTech and Moderna), particularly in adolescents and young adults. There has not been a similar reporting pattern observed after receipt of the Janssen COVID-19 Vaccine (Johnson & Johnson).
In most cases, patients who presented for medical care have responded well to medications and rest and had prompt improvement of symptoms. Reported cases have occurred predominantly in male adolescents and young adults 16 years of age and older. Onset was typically within several days after mRNA COVID-19 vaccination, and cases have occurred more often after the second dose than the first dose. CDC and its partners are investigating these reports of myocarditis and pericarditis following mRNA COVID-19 vaccination. -
2021-10-13 at 9:22 PM UTC in In Which Hogwarts House Do You Belong?
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2021-10-13 at 9:18 PM UTC in What's the deal with Strip Club Private Rooms?It sounds like your hand will be even sorer after you get home and abuse it.
