2019-08-02 at 2:39 AM UTC
the brain popping was you catching up on 5 years of development all at once
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post didn't die in a fire!
2019-08-02 at 3:02 AM UTC
Im beginning to think the neurogenesis trials especially in rats don't mean anything. Common sense would indicate that taking low dose meth everyday would not cause enough neurogesis to outweigh the negatives of it. I think seroquel even causes neurogenesis technically, but that doesn't mean that taking it won't cause more retardation despite that.
2019-08-02 at 3:20 AM UTC
i think the trials are meaningful for what happens to a persons brain on the cellular level. there are a million other factors going on in a persons head to contradict or support it but it gives a good base idea of what medicines actually cause healing effects in a mental state and what is harmful. for example seroquel causes neurogenesis but it also reduces cognition and reduces brain volume over time in high doses, but if you compare that to another substance that reduces cognition and brain volume but reduces neurogenesis as well, then the chemical would be ineffective compared to seroquel, so the ability to cause neurogenesis is related to its clinical ability to grow new cells.
the misconception is new brain cells = enhanced intelligence, but in reality it might just cause subtle effects that make a person's clinical picture seem less severe, as in healing the damage instead of being a brain steroid. the other misconception is that neurogenesis and related necessarily = good, because side effects need to be taken into account. like valproate has numerous protective effects but also can cause brain atrophy so the only way to judge if its good or bad overall is having the full picture of its neurological mechanisms
2019-08-02 at 3:31 AM UTC
im not sure on what information would allow two mechanisms to be compared in a cost:benefit analysis
like with gabapentin, does the blocking of synaptogenesis have more of a detrimental effect on a person than the enhancement of neurogenesis, or does the neurogenesis outweigh the blocking of synaptogenesis?
its mostly just theoretical for a future enhanced humanity, in the year 2019 and in reality its more important to just judge subjectively if it seems to help or not
2019-08-02 at 1:56 PM UTC
aldra
JIDF Controlled Opposition
lol, it's a list of drugs 'no-one should ever use'
tpain is not particularly addictive if dosed moderately and is prescribed in a good chunk of the world (mostly post soviet states I think). you only start getting into the danger zone if you repeatedly scale your dose up to get monged on it and/or start injecting
