***i did not write this, /u/socat2me on dread is the author.***
I felt like now was a good enough time as any to post this, this shit is pretty dangerous. This isn't a very refined post or technique like some of my guides, and I haven't had the time to run a lot of experiments to try and optimize the conditions or solvents. This isn't meant to be a really in-depth guide for now, it's meant to be a quick way to teach people the concept and be as accessible to as many people as possible and as simple as possible.
Disclaimer: Adding this section in just because I think some people have read this and gotten the wrong idea. This is analogous to just doing a simple filtration, evaporating the filtrate, and then repeating multiple times. I'm aware Xylazine is not insoluble in alcohols. This won't totally remove all the Xylazine, I was a little bit overzealous with the title which should probably have read a tek for removing "some" of it from your dope, however it will completely remove many of the other cuts and will significantly improve the quality of your dope, making it much more usable afterwards.
Xylazine is a weak base that reacts with acids to form salts, just like heroin or fentanyl. It's usually present as the hydrochloride,
Things you will need at bare minimum:
- Shitty xylazine dope
- Methanol (buy online)
- Acetone (buy online or at the hardware store, get something like klean strip that doesn't have additives)
- Some glass cups / flasks / beakers
- A glass oven-safe tray or dish
- Blow dryer / heat gun / fan
- Some kind of filtration mechanism. Read below to see what fits your situation. I always recommend the pipette and hand pumps to people. They're like a $30 investment and very worth it.
- Oven
Here's a quick run-down of the concept and a summary of the technique. Whatever drug you're partaking in is likely a hydrochloride salt. Maybe it's heroin hydrochloride, or maybe it's something stronger like one of the china white F# blends. These are pretty soluble in methanol. Xylazine hydrochloride is not all that soluble in methanol [or at least less so than the desired compounds]. This means if you crush up your dope really well and then add methanol to it, the dope will dissolve while a good portion of the Xylazine will not.
Summary of procedure so far: grind dope, add methanol. No more than 3 mL per gram.
enhancementING
Now you need to pass the resulting solution through a enhancement. This can be a lot of different things, at the most ghetto level, secure a coffee enhancement to a cup with a rubber band, make sure it has enough slack to where it droops down in the center to hold the solids and liquid. Pour the solution onto this and let it drain through. Save this liquid.
Some of you might be wondering if you can draw it up through a cotton the way you might enhancement a shot if you aren't using a syringe enhancement. This is actually the right kind of idea but methanol and most solvents will destroy the rubber plunger and plastic syringe too quickly. The cotton can also get clogged up with solids very quickly depending on how much of your dope is xylazine and other cuts.
One alternative is to invest in a glass syringe with a blunt tip needle that you can use exclusively for this purpose. Around 5 to 10mL would be a decent size. You can use this and just drop a new cotton ball in when the first one gets clogged.
Another, better method to using a glass syringe is to use a 10mL glass pipette and a pipette hand pump. Look on ebay/amazon for these they sell kits with 3. A larger hand pump will create more of a vacuum.
It works like a big syringe, you attach the pipette to the hand pump, push the tip into the cotton, and pull the plunger back to draw up liquid. Then you lightly tap the release button a few times to make sure you don't pull up the cotton when you with draw the whole thing.
At the most advanced level, use a buchner funnel and enhancement flask with 6-10 micron enhancement paper and some kind of vacuum source. You can just buy a full buchner vacuum filtration kit with funnel, flask, clamp, and hand pump included, or you can rig something up yourself.
Each time you do this, we'll call it a "pull". Whichever method you choose, you will want to add a little more methanol. Use half as much as the first time and then do the filtration again. Add this with the first liquid. Usually 3 pulls in total will do the trick.
Once you have your enhancemented liquid, unless it looks completely pristine, you should pass the liquid through your filtration method one more time, don't add more methanol, just enhancement the solution to remove any remaining solids. Use a fresh cotton/enhancement/etc don't pour your enhancemented solution back through the old solids or anything like that.
DRYING
Now pour this onto a glass, oven-safe tray. The more surface area the better. Shoot it with a blowdryer or heat gun to start evaporating it. For the fastest evaporation, try to hit it and work the air stream in such a way that it moves the liquid around in a circular pattern. If you can do this outside or on a patio that's ideal, if not just be mindful that methanol is flammable. Don't be stupid and turn the heat gun up to 1000 degrees and stick it right in the methanol and light yourself on fire. Just be reasonable and keep the heating element at a safe distance whatever you use and be mindful of how much vapor is accumulating around you if you aren't in a well ventilated space. If you aren't sure of yourself just use a fan and check back every hour or so.
Keep doing this until when you grab the tray and move it back and forth there is no liquid sloshing around.
[If you do this with a product that doesn't contain xylazine at all you can end up with a dry product right after evaporating the methanol. This will usually be pretty pure so be careful. Mind the weight before and after, if you end up with half the amount you started with it's probably 2x as strong. You can figure out the multiplier by dividing the starting weight by the end weight.]
SHITTY WET OIL >>> DRY SOLID
At this point you will most likely think you have failed and produced nothing but a bunch of wet/oily clear shit. This is because the product has oiled out, [here specifically this happens from it having a high water content. Xylazine HCl pulls in water aggressively and can form multiple different hydrates, so the more that's in your stuff the more of an issue the moisture is]. At this point the acetone comes in. Pour a little bit onto the tray and repeat the evaporation step. You're going to keep doing this acetone splashing and evaporating step until you start to see the white of a solid precipitating out. Think of the acetone as helping dry out the product.
If you have some kind of metal tool like what you might use to scoop your drugs / wax concentrate (or a spoon/butter knife) scraping the bottom of the tray to help mechanically agitate the solid can help speed up this last part.
When you don't see any more white appearing, as in when it seems to have all precipitated out, evaporate any remaining liquid until once again you can't slosh it around, this time you should have a damp solid. Now stick it in the oven at around 230F. Let it sit in there, checking on it every 8 minutes or so until it's dry enough to scrape with a razor and get a powder. Take it out and scrape it up. Unless you live in the desert or some shit you'll need to put this in some kind of jar or vial because it's pretty hygroscopic. If you just leave it on the plate or in a bag outside it will clump up.
If this clumping happens you'll have to put it in a shotglass or cup, pour acetone on it, crush it around with some tool and then pour it on the tray and dry it in the oven again.
These are also the same steps you should take if you heated/scraped it too early and it's still gooey.
And there you have it, I know there was a lot of details missing from this but this should give you a start. I've only had a chance to try this with methanol and anhydrous ethanol and the methanol worked better.
IMPORTANT NOTE: This also removes a lot of the polyhydric alcohol cuts like mannitol so be careful! You'll end up with a much stronger product. I'm repeating a similar note from earlier but pay attention to how much weight you've lost. This doesn't remove all the xylazine so if you end up with half the amount you started assume it's probably 2x as strong. You can figure out the multiplier by dividing the starting weight by the end weight. In reality the potency will be less than this but just for safety purposes use this as a starting estimation.
Hope this helps some people out there.
QUICK UPDATE:
I repeated this procedure again recently using a freshly opened bottle of anhydrous ethanol and found I was able to get the best results so far. I used a freshly opened bottle so it was very dry. If you're comfortable with drying solvent with 3A molecular sieve then know you can get better results by drying either alcohol with it first (sit overnight and then enhancement, decant, or distill before use). They absorb around 20% their weight when freshly regenerated.
My runner up recommendation as a desiccant (for the methanol) would be Magnesium Sulfate that's been made anhydrous by heating at 200C/392F. Let it cool down and then add it to the the methanol to a container that's sealed from air, agitate well and then enhancement after 30 minutes or so.
NEWEST ADDITION: Solubility data of possible candidate solvents
Unfortunately the solubilities change with the polymorphs of the xylazine hydrochloride. The anhydrous form and the hydrate are going to be the only ones I focus on.
%% Estimated Solubilities %%
Fentanyl Hydrlochloride
chloroform: 5mg/mL
dichloromethane: 6mg/mL
2-propanol: 10mg/mL
Xylazine HCl - Anhydrous form
chloroform: 2.5mg/mL
dichloromethane: 4.6mg/mL
2-propanol: 2mg/mL
Xylazine HCl - Hydrate
chloroform: 1.0mg/mL
dichloromethane: 2.3mg/mL
2-propanol: 0.8mg/mL
Note: I couldn't find anything for Heroin HCl, and the following values should be assumed computational unless a source is located for each one:
Separation will be maximized if the Xyl-HCl is allowed to form the main hydrate, then something like 99% or dry isopropyl alcohol is used.
To do this, take the mix or even a thoroughly dried product you obtained if you did this thread's parent procedure with something like methanol. Grind it in a mortar and pestle with a few drop of distilled water. Just enough to make a paste consistency. Spread this onto a glass tray then use a few drops to rinse the mortar an pour that on it to get everything. Spread onto a plate let air dry for a few days. At this point the Xylazine HCl should exist almost entirely as it's hydrate form.
Complete the procedure at this point using the isopropanol.
Isopropanol (isopropyl alcohol / 2-propanol) may be the ideal solvent. It makes sense. I got better performance with anhydrous ethanol than methanol, and of all the solvent comparisons, it is the most promising in terms of what it looks like on paper.
