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2024-07-10 at 3:07 PM UTC
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2024-07-10 at 3:11 PM UTC
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2024-07-10 at 3:27 PM UTCyahoo answer trolling was peak comedy
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2024-07-10 at 3:38 PM UTCMoney Girl Investment.
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2024-07-10 at 4:03 PM UTCMuhwhitey
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2024-07-10 at 5:31 PM UTCThe following users say it would be alright if the author of this post didn't die in a fire!
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2024-07-10 at 5:47 PM UTCLeaving forever
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2024-07-10 at 6:12 PM UTC
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2024-07-10 at 6:15 PM UTCThe following users say it would be alright if the author of this post didn't die in a fire!
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2024-07-10 at 6:18 PM UTCLame. Hehe
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2024-07-10 at 6:25 PM UTC
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2024-07-10 at 6:27 PM UTCwhat the fuck
NTRODUCTION:
The jedi-German chemist Julius von Braun published the seminal work that bears his name in 1907. For the better part of that century, the von Braun reaction has been the standard for N-demethylation of alkaloids, including the N-demethylation of oxycodone to make antagonist analogues such as naloxone. A little over a century later, a jedi-New Jerserian chemist, Duchess von D., would reverse engineer the work of Olofson and use the chloroformate-mediated N-demethylation of oxymorphone to naloxone, by using chloroformates to N-deallylate naloxone. As an appreciator of clever wordplay, the reverse rxn, the N-deallylation of naloxone, is hereby known as the Duchess von D-allylation.
When I speak of being a pioneer in the clandestine field, I’m certainly not the clandestine brainchild of these ideas. I’ve done much to simplify the procedures for the clandestine community, which is not always an easy task, but there is still room for improvement. I typically do not spend 20 pages discussing the nuances of a single transformation. Hopefully this will be a treat for detail hounds. I felt it was particularly applicable as it uses a non regulated precursor to access controlled intermediates that are near impossible to obtain via licit means. If one so desired, making oxymorphone instead of its N-phenethyl analogue, phenomorphone, would involve the simple substitution of methyl iodide in lieu of 2-phenethyl bromide during the N-alkylation step. The Duchess prefers phenomorphone for its much higher potency (compared to oxymorphone), the increased euphoria, and its unregulated nature (phenomorphone is not specifically listed in controlled substance laws).
I’ve spent the past 15 years consumed by the fiery passion of chemistry, which has defined my career as well as my clandestine destinies. Chemical creativity is different from that of the artistic varieties. There are very few truly brilliant chemists, i.e. the Linus Paulings of the world, who lay the foundations for and invent concepts that create new branches of the field. The best that most chemists can aspire to be is a highly resourceful, well-read, masterful technician. The ones w/ dozens of patents and their own firm, the top 1%, are brilliant masters of the pooled intellectual resources of the greater chemical community, being able to borrow related concepts and methodology from analogous rxns and apply them in novel ways to pre-existing commercially important compounds, or using known tools to develop novel molecules. We patent and invent “novel” methods/molecules, mostly, by borrowing related concepts and methodology from analogous rxns and applying these already established tools to a new molecule. I consider myself to be a highly right-brained individual. I’m more suited for creating art, music, and literature than a career in chemistry. Nonetheless, I find it richly rewarding and couldn’t imagine doing anything else. To me, the whole left-brained analytical process of science was a novelty and an adventure. It still is. At times however, as an artsy-creative type in a very serious analytical field, I feel like I’m a virtual machine running on an OS based on different architecture. The result may look the same, but the process is synthetic. What I cherish the most about my professional life are the more creative outlets and social interactions that come along with being part of a research group, such as presenting and networking at conferences, conveying our ideas in publications, persuading funding bodies to hop on board our train (it makes me feel like a gangster manipulating these pompous committees, board members and private/govt organizations to hand us their money…almost as good as it would feel if they signed a check made out to the Duchess herself), and, of course, I’m passionate as hell about teaching (and, surprisingly, it’s not always motivated by my underlying naughty desires to seduce members of the lacrosse team). But when I take off the lab coat and enter the privacy of my domicile, I feel that I can don my pointy black hat, perhaps a politically incorrect version of “Horny Heroin-Heroine Hermione goes to Hogwarts.” All of this wonderful knowledge, resources and tools at my disposal that can be retooled for a more subversive purpose (“subversive” only b/c society labels it so): for the benefit of members of the clandestine community, members of society, whom, like myself, have a shared secret passion. While the pursuit of better hedonism through chemistry, aka: opio-phoria, is not the same as witchcraft, historically speaking, there are plenty of analogies. They’ve both experienced prohibition, persecution and, thus, share the appeal of forbidden fruit. If you want the Duchess to explore something, simply tell her that she shouldn’t do it. [Footnote #1 in Bibliography]
Curiosity may kill cats, but that’s b/c, unlike me, they only have nine, instead of 40+ lives. They plan their epic explorations of the feline world like pussies. I plan my exploration of the opio-verse like a girl scout: preparing for feral felines disasters, feline distemper, and fentalogue hiccups. When engaged in a clandestine field where self-experimentation is the norm and the development of dependencies and tolerances are pretty much guaranteed, it helps to bring along a chaperone; in my case, a “naloxone chaperone” aka: nalaperone. This traditionally takes the form of a side-kick, partner in crime, partner-of-mine, or, if you believe in naloxone-toting angels, then (perhaps) partners-divine.
Maybe I shouldn’t assume that all of you have seen that cute PSA promoting “responsible analoging,” the one w/ that cute catchphrase:
Would you play a saxophone with a reed made from a scone?
Would you loan a suboxone under the tongue of a sista who’s on methadone?
Would you ride bikes with Eliot w/o helping E.T. Phone Home?
“Auntie’s syringes ain’t daggers,” you remind your 4 y.o. Nephew, “Just leave that shit alone,”
All Niece-nephew dagger fights are accompanied by an auntie w/ nappies and some naloxone,
Yo’ hair ain’t turf; yo’ head ain’t no astro-dome, it’s more than a mere hollow sphere encased in shiny bone,
So when you’re playing the needle-prick-a-phone w/ a novel analogue of oxymorphone,
Or attending poke-a-dilly-circus accompanied by 14-cinnamoyloxycodeinone,
Or wanna safely stone on your latest bezitramide derived ketone,
Don’t go playing Morpho-polo w/o an appointed nalaperone.
To safely navigate intravenous hide-n-seek in the realm of the opio-unknown,
Don’t be no fool, nigga, please don’t analogue alone -
2024-07-10 at 9:37 PM UTCOooohhh Barracudaaaaa 🎵
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2024-07-10 at 10:02 PM UTC"Welcome to the suburbs. There is no escape."
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2024-07-11 at 5:25 AM UTC
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2024-07-11 at 6:59 AM UTCgoat meat .
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2024-07-11 at 9:56 AM UTCI'm thinking, She's one bangin hot MILF.
No I meant, I'm thinking you could all learn a thing or two from this
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2024-07-11 at 7:21 PM UTCThe incident with that incel grabbing my arm three times appeared in my dream ln and now I'm convinced time doesn't heal. Things that happened years ago still show up in my dreams.
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2024-07-11 at 7:21 PM UTCJust realised it's 8pm and I need to buy food.
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2024-07-11 at 7:21 PM UTC
The following users say it would be alright if the author of this post didn't die in a fire!
