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Some O.G. Totseans - Chime up if you know what they up to or if you happen to be them with a new username
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2018-12-17 at 5:31 PM UTC
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2018-12-17 at 5:53 PM UTClmao at "A water soluble drug will dissolve straight through the nasal membrane and into the brain in just a few seconds" that so many level of bullshit
yeah dude and mushrooms make your fucking brain bleed. jesus christ.
it will go RIGHT INTO YOUR FUCKING BRAIN DUDE
no the blood brain barrier isn't a thing, if you snort drugs it goes STRAIGHT TO YOUR BRAIN -
2018-12-17 at 6:07 PM UTC
Originally posted by Rizzo in a box lmao at "A water soluble drug will dissolve straight through the nasal membrane and into the brain in just a few seconds" that so many level of bullshit
yeah dude and mushrooms make your fucking brain bleed. jesus christ.
it will go RIGHT INTO YOUR FUCKING BRAIN DUDE
no the blood brain barrier isn't a thing, if you snort drugs it goes STRAIGHT TO YOUR BRAIN
Jesus Christ you people are stupid. Have you ever snorted cocaine? Hits you instantly doesn't it? That's why you snort it, because its the fastest route. It works that fast because it is a hydrochloride salt, so its soluble.
I mean think about it, if it took over half an hour to affect Casper when he snorted it earlier, yet just swallowing the tablets takes barely 20 minutes, then really what is the point of snorting it? What is the advantage?
Other than "yeah look at me I'm snorting, I look like tony Montana herp derp".
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2018-12-17 at 6:08 PM UTC
Originally posted by Narc Jesus Christ you people are stupid. Have you ever snorted cocaine? Hits you instantly doesn't it? That's why you snort it, because its the fastest route. It works that fast because it is a hydrochloride salt, so its soluble.
I mean think about it, if it took over half an hour to affect Casper when he snorted it earlier, yet just swallowing the tablets takes barely 20 minutes, then really what is the point of snorting it? What is the advantage?
Other than "yeah look at me I'm snorting, I look like tony Montana herp derp".
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no dude, snorting does not, and has never hit you INSTANTLY. why the FUCK do you think people fucking inject drugs? which by the way, injecting still takes a few seconds to actually kick in. even injecting is not "instant", I could write entire poems about the space of time where you pull the plunger down but the drugs haven't hit and you're just looking at this needle.
you're so fucking dumb it boggles the mindThe following users say it would be alright if the author of this post didn't die in a fire! -
2018-12-17 at 6:12 PM UTCYou fucking Muppet. By instant I'm talking a few seconds, as opposed to 15+ minutes through oral route.
You gotta be trollin to be this level of stupid.
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2018-12-17 at 6:16 PM UTCSmoke a joint and clam down you niggers.
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2018-12-17 at 6:49 PM UTCI mean instant coffee still takes a few moments to make. Its not actually instant.
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2018-12-17 at 6:57 PM UTC
Originally posted by Narc Jesus Christ you people are stupid. Have you ever snorted cocaine? Hits you instantly doesn't it? That's why you snort it, because its the fastest route. It works that fast because it is a hydrochloride salt, so its soluble.
I didn't say it started working in 30 min. I said in 30 minutes it became apparentl I was incredibly fucked up off 2mg- which for a 350 lb dude, is a pretty small dose. The question at hand was whether benzos work insufflated at ALL. Not conclusive, but it seems that it does. That was it. Not whether it's more efficient or whatever the fuck. I personally have to take 4-6mg orally for proper effects, and usually if I'm having an anxiety attack or in withdrawals, it takes me an hour to an hour and a half to feel okay.
I mean think about it, if it took over half an hour to affect Casper when he snorted it earlier, yet just swallowing the tablets takes barely 20 minutes, then really what is the point of snorting it? What is the advantage?
Other than "yeah look at me I'm snorting, I look like tony Montana herp derp".
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THAT was the point.
While bioavailability isn't as good, inhaled, insufflated and sublingual are supposed to provide 20% higher peak plasma concentrations.
I'm not sure what you're all pissy about. -
2018-12-17 at 7:01 PM UTCYou'd have to have someone totally. Naive to the substance and with low body weight to be able to observe the effects quickly. Otherwise there are about a thousand different factors that can effect subjective perception of whether the drug is working yet or not.
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2018-12-17 at 7:20 PM UTCnuke the UK
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2018-12-17 at 7:52 PM UTCWhatever, you guys go fuck your noses up for no extra benefit what so ever then. Like I even care.
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2018-12-17 at 8:23 PM UTCLol. Dun be mad mate. Wes just knobbin wit yaz.
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2018-12-17 at 8:26 PM UTC
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2018-12-17 at 8:51 PM UTC
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2018-12-17 at 8:51 PM UTC
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2018-12-17 at 8:52 PM UTC
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2018-12-17 at 8:52 PM UTC
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2018-12-17 at 9:03 PM UTC
Originally posted by Rizzo in a box no dude, snorting does not, and has never hit you INSTANTLY. why the FUCK do you think people fucking inject drugs? which by the way, injecting still takes a few seconds to actually kick in. even injecting is not "instant", I could write entire poems about the space of time where you pull the plunger down but the drugs haven't hit and you're just looking at this needle.
you're so fucking dumb it boggles the mind
Said the IV drug junkie -
2018-12-17 at 9:20 PM UTC
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2018-12-18 at 1:51 AM UTCI'm gonna fuck everyone here in da'butt
