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made some poppy seed tea today
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2017-07-10 at 2:16 PM UTC
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2017-07-10 at 2:20 PM UTCThat's far beyond paranoia. He said it feels like PCP to him.
Do you remember how long he's been smoking smoking syncans, the ridiculous amounts he used to use? Who knows what it's done to him, particularly considering the age range when he was usng. -
2017-07-10 at 2:21 PM UTC
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2017-07-10 at 2:33 PM UTC
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2017-07-10 at 3:03 PM UTC
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2017-07-10 at 3:18 PM UTCITT: Things that didn't happen
You didn't get high off random poppy seeds, faggot, dream on. -
2017-07-10 at 3:30 PM UTC
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2017-07-10 at 3:31 PM UTC
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2017-07-10 at 3:37 PM UTC
Originally posted by Helladamnleet ITT: Things that didn't happen
You didn't get high off random poppy seeds, faggot, dream on.
What the fuck is with this forum and people all of a sudden denying things that are obvious? You don't believe poppies contain opium? I'm not going to argue with you but you're an idiot if you think that -
2017-07-10 at 3:38 PM UTC
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2017-07-10 at 3:41 PM UTCI don't think so.
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2017-07-10 at 3:43 PM UTC
Originally posted by Malice It's not actually an SSRE! The basic information published about drugs, even the classification, can be immensely inaccurate and misleading. It's primarily a glutamatergic modulator at therapeutic doses.
The neurobiological properties of T-PAIN (Stablon): from monoamine hypothesis to glutamatergic modulation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902200/
It's even been confirmed to be safe to combine with MAOIs, producing no interaction, despite serotonergic drugs being incredibly dangerous to combine with them, deadly.
Because of its effect of glutamatergic modulation, it can lower excessive glutamate levels. Hydro has a severe anxiety disorder, which is extremely common in Asperger's, having a 65% comorbidity, and being of a different nature than the anxiety that afflicts neurotypicals. A deficit in the GABAergic pathway has been confirmed, leading to far lower effective GABA levels. As for glutamate, hyperglutamatergia is another core neurological aspect. There are differences in GAD, glutamic acid decarboxylase, which converts glutamate into GABA, in regions of the brain. As well as the metabotropic glutamate receptors, mglur. Epilepsy has a 25% comorbidity with ASD, and the core aspect of the sizable effective glutamate/GABA imbalance plays a strong key role in this.
There are other aspects that contribute to anxiety and epilepsy in Asperger's such as serotonergic deficiency and its effect being mediated by certain subreceptors, such as the 5-HT1A receptor implicated in anxiety, which the anxiolytic Buspirone (Pitiful efficacy.) agonizes. Activation of 5-HT1a also produces an anticonvulsant effect and increases the seizure threshold (Positive effect.). Along with the right hemisphere of the amygdala, which deals primarily with negative emotions, being hypertrophied an average of 20%, along with connections to the prefrontal cortex being 50% weaker on average, leading to an excessively long signaling period, well after any perceived danger, that is, anything that triggers the fear response/elicits amygdala activity related to danger or negativity will cause a signal that is amplified, much stronger than the response of a neurotypical without an anxiety disorder, that will also remain for substantially longer. It may also possess increased cell density. The amygdala also has the highest density of GABAa receptors in the brain, providing a crucial insight when connected to the effective deficiency of GABA stemming from a pathway deficit. Of course it's long been known that the amygdala plays a pivotal role in epilepsy.
Post last edited by Malice at 2017-07-10T09:31:02.481827+00:00
There is a reason I said functionally, you pedantic autistic fookin
As far as I'm aware, it still ACTS as an SSRE, and I don't think it's lack of interaction with an MAOI means that it is safe to take in the ballsfuckingly high doses people like hydro take it at. She used to eyeball doses with the tip of a spoon like its fun dip.
I mean, you act like 5HT and glutamine/GABA are some kind of wholly separate system, and that if you've got one you can't have the other. They are intrinsically entwined and it's the reason there was confusion in the first place. Also the whole being a trycilic thing.
Plus, all of these studies are with normal therapeutic doses of T-PAIN. I'm not aware of any megadosing studies. Dosing high could very well have negative or even paradoxical effects. -
2017-07-10 at 3:44 PM UTC
Originally posted by greenplastic What the fuck is with this forum and people all of a sudden denying things that are obvious? You don't believe poppies contain opium? I'm not going to argue with you but you're an idiot if you think that
The point of it is that you could've got seeds that were like 20x as potent elsewhere.
Bill Krozby mentioned taking an lb+ for his tea but that would fucking kill you with any good bag of seeds.
Also there is the issue of method.
"SWIM" found that the best thing to do is to barely cover the top of the seeds in your cup, add lemon juice, then mix them. This way they scrape together. Do this twice while mixing for two minutes each and strain. Then SWEMMM fills the cup and stirs for one minute and strains. I
Er
I mean SWIM
SWIM finds that the seeds scraping together in low water, and the addition of lemon juice or some kind of acid (have heard of people using pickle juice even) are absolutely essential.
Post last edited by 霍比特人 at 2017-07-10T15:48:05.032343+00:00 -
2017-07-10 at 3:51 PM UTC
Originally posted by Bill Krozby ^of course anyone get them cheap on line you ree ree. but for some its easier drive a few blocks. I mix mine with whyte grape fruit juice and let it sit and then shake it up, i pour some of the juice out and put a funnel and pour a 1.25 lbs of seeds down and im good for awhile.
Bill Krozby you're a piece of shit but if you ever get any quality seeds do not use 1.25lb. This is how people die. With a good bag SWIM can use like 70g-100g with 15-30g being threshold range. There are 453 grams per lb. I've heard of much stronger stuff from abroad too. I'm just talking about the regular kosher stuff thats widely available online. If you get seeds bred for opioid content its gonna be way more potent than this. -
2017-07-10 at 6:34 PM UTC
Originally posted by greenplastic What the fuck is with this forum and people all of a sudden denying things that are obvious? You don't believe poppies contain opium? I'm not going to argue with you but you're an idiot if you think that
Not the random ass ones he bought at the store, no. Why do you think only certain strains are frowned upon? Next you'll be saying you can smoke the salvia they sell at walmart. -
2017-07-10 at 6:37 PM UTC
Originally posted by Helladamnleet Not the random ass ones he bought at the store, no. Why do you think only certain strains are frowned upon? Next you'll be saying you can smoke the salvia they sell at walmart.
Certain strains are frowned upon? What does that even mean? Papaver Somniferum has morphine and other alkaloids. If the seeds are unwashed or poorly washed, they will be coated with small amounts of these alkaloids. The poppy seeds at the middle eastern market were imported from India and definitely not washed, or at least not washed well enough to get all the alkaloids off. I don't know why that's so hard to believe. -
2017-07-10 at 6:39 PM UTC
Originally posted by 霍比特人 The point of it is that you could've got seeds that were like 20x as potent elsewhere.
Bill Krozby mentioned taking an lb+ for his tea but that would fucking kill you with any good bag of seeds.
Also there is the issue of method.
"SWIM" found that the best thing to do is to barely cover the top of the seeds in your cup, add lemon juice, then mix them. This way they scrape together. Do this twice while mixing for two minutes each and strain. Then SWEMMM fills the cup and stirs for one minute and strains. I
Er
I mean SWIM
SWIM finds that the seeds scraping together in low water, and the addition of lemon juice or some kind of acid (have heard of people using pickle juice even) are absolutely essential.
Post last edited by 霍比特人 at 2017-07-10T15:48:05.032343+00:00
Where? How do you know the potency of the seeds I got if I got them from a local market that you've never been to?
The acid is definitely not essential but maybe I'll give it a go next time. -
2017-07-10 at 6:42 PM UTC
Originally posted by RisiR † I don't think so.
normal -
adjective
1.
conforming to a standard; usual, typical, or expected.
It's the standard for people to be non-albino, but it is also expected that a certain amount of the population will be albino. Care to explain where I'm confused here?
Let me guess, your answer is going to be "ur dum u need 2 reed moar about syence if u tink dat" -
2017-07-10 at 6:43 PM UTC
Originally posted by greenplastic Certain strains are frowned upon? What does that even mean? Papaver Somniferum has morphine and other alkaloids. If the seeds are unwashed or poorly washed, they will be coated with small amounts of these alkaloids. The poppy seeds at the middle eastern market were imported from India and definitely not washed, or at least not washed well enough to get all the alkaloids off. I don't know why that's so hard to believe.
Whatever, kid, you clearly don't know what you're talking about and I'm not coming back to this thread to argue with you. I've forgotten more about poppies than you'll ever know. My dad had the local police knocking at the door every year checking his poppies for the strain that actually contains a useful amount of anything. Your common ones don't possess nearly enough of the chemical needed to do anything useful. -
2017-07-10 at 6:48 PM UTC
