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question about eating lsd
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2017-07-06 at 2:25 PM UTC
Originally posted by -SpectraL If your palm would have been just a bit more sweaty, it would have. Not talking about geltabs. Talking about blotters and microdots.
So to be clear, what you are saying is that if I wear latex gloves and place an LSD blotter in a gel cap, making sure that the blotter does not touch the outside of the gelcap at all, and then swallow the gel cap, I will not trip because the chlorine in my stomach will destroy the LSD immediately? -
2017-07-06 at 2:29 PM UTC
Originally posted by greenplastic So to be clear, what you are saying is that if I wear latex gloves and place an LSD blotter in a gel cap, making sure that the blotter does not touch the outside of the gelcap at all, and then swallow the gel cap, I will not trip because the chlorine in my stomach will destroy the LSD immediately?
You won't trip until the digestive juices break through the gelcap, and even then, any food already in there is going to dilute it down, so that would be a terrible way to ingest acid. If you're going to swallow it, just use a blotter or a microdot, and it will be absorbed before it even reaches the stomach. -
2017-07-06 at 2:38 PM UTC
Originally posted by -SpectraL You won't trip until the digestive juices break through the gelcap, and even then, any food already in there is going to dilute it down, so that would be a terrible way to ingest acid. If you're going to swallow it, just use a blotter or a microdot, and it will be absorbed before it even reaches the stomach.
Then even if you were correct, it's still not an answer to the question of why LSD would not break down immediately in the stomach. -
2017-07-06 at 2:40 PM UTC
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2017-07-06 at 2:43 PM UTC
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2017-07-06 at 2:49 PM UTC
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2017-07-06 at 2:55 PM UTC
Originally posted by -SpectraL "…why don't the chlorine atoms murk (oxidize) the LSD molecules real quick, rendering it ineffective?"
Because the acid is absorbed way before any such event can occur.
Yes, that's what you said, and then I posed a scenario where the LSD could not possibly be absorbed prior to hitting the stomach, and you said:
"It will still break down in the stomach as normal. Nothing will be counteracted."
My question is about the normal process of LSD breaking down in the stomach. Answering that it does it the same as normal is not a meaningful answer. -
2017-07-06 at 2:57 PM UTC
Originally posted by Totse 2001 related/unrelated
Ken Kesey and the Merry Pranksters lived communally at Kesey's homes in California and Oregon, and are noted for the sociological significance of a lengthy road trip they took in the summer of 1964, traveling across the United States in a psychedelic painted school bus called Furthur or Further, organizing parties and giving out LSD.[1] During this time they met many of the guiding lights of the mid-1960s cultural movement and presaged what is commonly thought of as hippies with odd behavior, tie-dyed and red, white and blue clothing, and a renunciation of the normal society, which they dubbed The Establishment. Tom Wolfe chronicled their early escapades in The Electric Kool-Aid Acid Test; Wolfe also documents a notorious 1966 trip on Further from Mexico through Houston, stopping to visit Kesey's friend, novelist Larry McMurtry. Kesey was in flight from a drug charge at the time. [2] Notable members of the group include Kesey's best friend Ken Babbs, Carolyn "Mountain Girl" Garcia, Lee Quarnstrom, and Neal Cassady. Stewart Brand, Paul Foster, Dale Kesey (his cousin), George Walker, the Warlocks (now known as the Grateful Dead), Del Close (then a lighting designer for the Grateful Dead), Wavy Gravy, Paul Krassner, and Kentucky Fab Five writers Ed McClanahan and Gurney Norman (who overlapped with Kesey and Babbs as creative writing graduate students at Stanford University) were associated with the group to varying degrees.[citation needed]
These events are also documented by one of the original pranksters, Lee Quarnstrom, in his memoir titled When I Was a Dynamiter.
Contents
Thanks for the tidbit.
Magic Bus gives clarity to the astonishing example of proper class within times of cross lateral division. -
2017-07-06 at 3:09 PM UTCReactivity and degradation
"LSD," writes the chemist Alexander Shulgin, "is an unusually fragile molecule… As a salt, in water, cold, and free from air and light exposure, it is stable indefinitely."[13]
LSD has two labile protons at the tertiary stereogenic C5 and C8 positions, rendering these centres prone to epimerisation. The C8 proton is more labile due to the electron-withdrawing carboxamide attachment, but removal of the chiral proton at the C5 position (which was once also an beta proton of the parent molecule tryptophan) is assisted by the inductively withdrawing nitrogen and pi electron delocalisation with the indole ring.[citation needed]
LSD also has enamine-type reactivity because of the electron-donating effects of the indole ring. Because of this, chlorine destroys LSD molecules on contact; even though chlorinated tap water contains only a slight amount of chlorine, the small quantity of compound typical to an LSD solution will likely be eliminated when dissolved in tap water.[13] The double bond between the 8-position and the aromatic ring, being conjugated with the indole ring, is susceptible to nucleophilic attacks by water or alcohol, especially in the presence of light. LSD often converts to "lumi-LSD", which is inactive in human beings.[13]
A controlled study was undertaken to determine the stability of LSD in pooled urine samples.[88] The concentrations of LSD in urine samples were followed over time at various temperatures, in different types of storage containers, at various exposures to different wavelengths of light, and at varying pH values. These studies demonstrated no significant loss in LSD concentration at 25 °C for up to four weeks. After four weeks of incubation, a 30% loss in LSD concentration at 37 °C and up to a 40% at 45 °C were observed. Urine fortified with LSD and stored in amber glass or nontransparent polyethylene containers showed no change in concentration under any light conditions. Stability of LSD in transparent containers under light was dependent on the distance between the light source and the samples, the wavelength of light, exposure time, and the intensity of light. After prolonged exposure to heat in alkaline pH conditions, 10 to 15% of the parent LSD epimerized to iso-LSD. Under acidic conditions, less than 5% of the LSD was converted to iso-LSD. It was also demonstrated that trace amounts of metal ions in buffer or urine could catalyze the decomposition of LSD and that this process can be avoided by the addition of EDTA. -
2017-07-06 at 3:19 PM UTC
Originally posted by -SpectraL Reactivity and degradation
"LSD," writes the chemist Alexander Shulgin, "is an unusually fragile molecule… As a salt, in water, cold, and free from air and light exposure, it is stable indefinitely."[13]
LSD has two labile protons at the tertiary stereogenic C5 and C8 positions, rendering these centres prone to epimerisation. The C8 proton is more labile due to the electron-withdrawing carboxamide attachment, but removal of the chiral proton at the C5 position (which was once also an beta proton of the parent molecule tryptophan) is assisted by the inductively withdrawing nitrogen and pi electron delocalisation with the indole ring.[citation needed]
LSD also has enamine-type reactivity because of the electron-donating effects of the indole ring. Because of this, chlorine destroys LSD molecules on contact; even though chlorinated tap water contains only a slight amount of chlorine, the small quantity of compound typical to an LSD solution will likely be eliminated when dissolved in tap water.[13] The double bond between the 8-position and the aromatic ring, being conjugated with the indole ring, is susceptible to nucleophilic attacks by water or alcohol, especially in the presence of light. LSD often converts to "lumi-LSD", which is inactive in human beings.[13]
A controlled study was undertaken to determine the stability of LSD in pooled urine samples.[88] The concentrations of LSD in urine samples were followed over time at various temperatures, in different types of storage containers, at various exposures to different wavelengths of light, and at varying pH values. These studies demonstrated no significant loss in LSD concentration at 25 °C for up to four weeks. After four weeks of incubation, a 30% loss in LSD concentration at 37 °C and up to a 40% at 45 °C were observed. Urine fortified with LSD and stored in amber glass or nontransparent polyethylene containers showed no change in concentration under any light conditions. Stability of LSD in transparent containers under light was dependent on the distance between the light source and the samples, the wavelength of light, exposure time, and the intensity of light. After prolonged exposure to heat in alkaline pH conditions, 10 to 15% of the parent LSD epimerized to iso-LSD. Under acidic conditions, less than 5% of the LSD was converted to iso-LSD. It was also demonstrated that trace amounts of metal ions in buffer or urine could catalyze the decomposition of LSD and that this process can be avoided by the addition of EDTA.
Interesting, so according to Shulgin, if I do the gel cap method I described earlier, I should not trip at all because the LSD would be immediately destroyed by chlorine ions in the stomach.
I still suspect that that is wrong though. I'll test it soon. -
2017-07-06 at 3:25 PM UTCNo, it would not be immediately destroyed. Like I said before, the acid will have already been absorbed into the bloodstream before the chlorine could even begin to act on it.
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2017-07-06 at 3:26 PM UTC
Originally posted by -SpectraL No, it would not be immediately destroyed. Like I said before, the acid will have already been absorbed into the bloodstream before the chlorine could even begin to act on it.
If the LSD is inside a gel cap it would not come into contact with any part of your skin before it is inside your stomach which is full of chlorine ions. Where are you suggesting the LSD would be absorbed before it hits the stomach? -
2017-07-06 at 3:30 PM UTCThis thread is seriously fucking painful.
Spectral is trolling you greenplastic
Either that or he's genuinely this retarded. -
2017-07-06 at 3:46 PM UTC
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2017-07-06 at 4:21 PM UTC
Originally posted by greenplastic If the LSD is inside a gel cap it would not come into contact with any part of your skin before it is inside your stomach which is full of chlorine ions. Where are you suggesting the LSD would be absorbed before it hits the stomach?
Well, I guess that would depend where in the stomach the acid ends up after being released from the gel cap. If it was released in contact with the walls of the stomach, the blood vessels there would absorb it in a matter of seconds. If it was released in the center of the stomach, then the chlorine may get the chance to neutralize it. It's all about if contact with the blood vessels are made or not, and when. -
2017-07-06 at 4:46 PM UTC
Originally posted by -SpectraL Well, I guess that would depend where in the stomach the acid ends up after being released from the gel cap. If it was released in contact with the walls of the stomach, the blood vessels there would absorb it in a matter of seconds. If it was released in the center of the stomach, then the chlorine may get the chance to neutralize it. It's all about if contact with the blood vessels are made or not, and when.
Isn't the stomach lining covered in mucous to protect it from the hydrochloric acid? -
2017-07-06 at 6:04 PM UTC
Originally posted by greenplastic Well at least he's trying, unlike the self professed physics experts on this website
"physics"
Jesus Christ.
Anybody who knows the slightest bit of pharmacology knows that spectral is talking total shit. I gave you all you needed to know in my first post in this thread.
This is like watching kids play in the sand and talk about architecture. -
2017-07-06 at 6:07 PM UTC
Originally posted by 霍比特人 "physics"
Jesus Christ.
Anybody who knows the slightest bit of pharmacology knows that spectral is talking total shit. I gave you all you needed to know in my first post in this thread.
This is like watching kids play in the sand and talk about architecture.
You seem soured. -
2017-07-06 at 6:13 PM UTCChemistry is not legos, spectral. Hydrochloric acid is its own thing. It is not hydrogen + chlorine when it comes to chemical reactions. If this were true, drinking piss would lead you to spew out a bunch of chlorine gas because of the ammonia. But obviously that doesn't happen.
This is highschool chemistry, guys.The following users say it would be alright if the author of this post didn't die in a fire! -
2017-07-06 at 6:28 PM UTC
Originally posted by 霍比特人 "physics"
Jesus Christ.
Anybody who knows the slightest bit of pharmacology knows that spectral is talking total shit. I gave you all you needed to know in my first post in this thread.
This is like watching kids play in the sand and talk about architecture.
"Because chemistry doesn't work like that" is not a meaningful answer. Spectral did better than you in that regard.
Chemistry is basically just a different branch of physics. It's clear you are either the least knowledgable person in this thread or trolling.
