What do you think is the easiest drug to create?

1. 2024-07-09 at 8:06 AM UTC

   #21
   

   blackbird Tuskegee Airman
   An LSA or benzedrex extraction.
2. 2024-07-09 at 11:55 AM UTC

   #22
   

   the man who put it in my hood Black Hole [miraculously counterclaim my golf]
   uhm yeah okay guys taking one chemical and modyfying it from pills or whatever isn't really "creating" a drug now is it?
   
   

   Aceglutamide aluminum
   (Psychostimulant)
   
   https://en.m.wikipedia.org/wiki/Aceglutamide
   
   https://www.kenresearch.com/blog/201...ina-2010-2019/
   
   N-acetyl-L-glutamine (buy from amazon)
   Aluminum Isopropoxide (make from aluminum powder sold as moss killer)
   
   37 grams glutaine in 1L water 40°C. 900ml isopropanol w/ 40.8g aluminum with stirring. 10 minutes. enhancement and concentrate under reduced pressure. Isopropanol is added and salt crystallises out. enhancement and dry.
   
   Dimethyl Tubocurarine iodide
   (Muscle relaxer)
   
   https://en.m.wikipedia.org/wiki/Dime...inium_chloride
   
   Curare (buy on the internet/grow it)
   methyl iodide (even I have some of this laying around)
   
   Vanillic acid diethylamide (VSD)
   (CNS stimulant)
   
   http://www.sigmaaldrich.com/catalog/...g=fr®ion=BE
   
   
   Made like LSD but starting from Vanillin.

3. 2024-07-09 at 8:44 PM UTC

   #23
   

   the man who put it in my hood Black Hole [miraculously counterclaim my golf]
4. 2024-07-16 at 12:40 AM UTC

   #24
   Lanny Lanny African Astronaut
   Not a chemist. wouldn't know. wouldn't try.
   
   I mean I guess knowing how to during a slide off the grid might come in handy but how would you order the chemicals to make shit like Levothyroxine or Adderall or one of the many drugs im on
   
   I'd be better off breaking into a Rx store and finding whatever was left behind if it ever came to that
5. 2024-07-16 at 1:18 AM UTC

   #25
   

   the man who put it in my hood Black Hole [miraculously counterclaim my golf]
   I am not a professionally trained chemist. I am what's know in the underground chemistry circles as a "chemhack" which I think sounds cool (it's mostly used as an insult to shake and bake meth cooks that think they know what they're doing)
   
   Check this out fellas, HOW TO MAKE NITRIC ACID WITHOUT ANY DANGEROUS OR RESTRICTED CHEMICALS!!! MAKE HIGH % CONCENTRATION NITRIC ACID!!!! USE$FUL FOR EXPLOSIVES!!!! AND MANY OTHER THINGS!!!!! REVOLUTIONARY!!!
   
   
6. 2024-07-16 at 1:28 AM UTC

   #26
   

   the man who put it in my hood Black Hole [miraculously counterclaim my golf]

   Originally posted by Lanny Lanny I mean I guess knowing how to during a slide off the grid might come in handy but how would you order the chemicals to make shit like Levothyroxine or Adderall or one of the many drugs im on

   amphetamine is easy, it's made like meth but slightly different. I think the medical grade stuff is 100% dextro amphetamine which is made different than "street grade" because it's optically pure but it's pretty simple to make optically pure drugs i.e 100% D-meth from ephedrine reduction vs 50% d-l meth from p2p
   
   

   A mixture of 40 g (0.3 mole) phenylacetone, 200 ml ethanol, 200 ml 25% ammonia, 40g (1.5 mole) Al-grit and 0.3 g (1 mmol) HgCl2 is warmed with vigorous stirring until reaction takes place, after which warming is stopped immediately. Cooling should be applied if the reaction becomes too violent. When the violence of the reaction has diminished, the mixture is refluxed with vigorous stirring for about 2 hr, concentrated in vacuo to 200 ml and poured into ice water, alkalinized with 120 g KOH, and extracted with ether. The extractions are treated with 20% HCl, the resulting water layer alkalinized and extracted with 150 ml ether. The organic layer is dried over Na2SO4, the ether evaporated, and the residue distilled in vacuo. Yield: 12.5 g (30%).
   
   Preparation of amphetamine sulfate yielded 96-98% product with a purity of 99.2-99.8% (USP grade).

   
   wikipedia says

   Industrially, levothyroxine is made by chemical synthesis. Tyrosine is a common starting material. The produced hormone is incorporated into drugs as its sodium salt, levothyroxine sodium. Solid drugs such as tablets contain the pentahydrate form of the salt

   
   
   according to
   https://patents.google.com/patent/US9428444B2/en
   

   Preparation of Levothyroxine
   RBF was charged with 100 gms of 3,5-Diiodothyronine and 1000 ml of methanolic monomethylamine at 25-30° C. and stirred for 15-20 min to get clear solution. The reaction mixture was then cooled to −8 to 0° C., and added with Iodine solution at −8 to 0° C. over a period of 2 hrs and maintained for 30-45 min at −8 to 0° C. The temperature of the reaction mixture was slowly brought to 15-20° C. and charged with 100 gms of sodium bisulphite followed by 300 gms of Potassium dihydrogen phosphate. The temperature of the reaction mixture was adjusted to 25-30° C. and maintained for 30-45 min at 25-30° C. The resultant mixture was enhancemented and washed with 200 ml of water followed by 200 ml of acetonitrile, dried under vacuum for 12-15 hrs at 55-60° C. to get 130 gms of Levothyroxine with purity NLT 98.5% and yield of 84.5-91.2%.
   Example-4
   Preparation of Levothyroxine Sodium
   RBF was charged with 1000 ml of n-Butanol and 100 gms of Levothyroxine, cooled the contents to 5° C. and charged with 10 ml of concentrated sulphuric acid to get clear solution. The reaction mixture was enhancemented through 0.45 micron membrane enhancement and the filtrate was purged with ammonia gas to attain pH 8. The mixture was then heated to 60-65° C. and maintained for 1 hr at 60-65° C., followed by cooling to 40-45° C. and filtration at 45° C. The filtrate was then washed with 200 ml of hot n-Butanol. The wet cake is then charged with 250 ml of 1.5% aqueous Sodium hydroxide solution at 25-30° C. (pH maintained at 10), Followed by Slow addition of 800 ml of 1-propanol over a period of 10-15 min at 25-30° C., heated to 60-65° C. and maintained for 1 hour. Further the reaction mixture is cooled to 25-30° C. and maintained for 1 hour, enhancemented and washed with 100 ml of 1-propanol followed by vacuum drying at 45-50° C. for 12-15 hrs to get 85 gms of pure Levothyroxine sodium of 78-83% yield.

   
   I don't know anything about "Levothyroxine sodium" does it say SODIUM on the bottle? That might be the only salt form ...just checked.. HTS is on levo I checked her bottle it says NA which means SODUIM i.e NaCl = Salt so YES YOU !!MUST !!!MAKE THE SODIUM SALT
   
   I rate part 1 of this reaction a 5/10 difficulty
   
   I rate part 2 (the sodium salt) somewhere around a 7-8 in difficulty. Molten 1-proponal sounds kinda sketch, and n-butanol is not easily available generally but if you can figure those out it's pretty simple I can follow this entire reaction and i'm retarded.
   
   The adderall synth is 4/10 in difficult
7. 2024-07-16 at 2:46 AM UTC

   #27
   Lanny Lanny African Astronaut
   You're speaking latin to me. I failed in Chemistry. really wish I hadn't
8. 2024-07-16 at 2:55 AM UTC

   #28
   

   the man who put it in my hood Black Hole [miraculously counterclaim my golf]
   lol I dropped out of highschool, I remember doing the worksheets for balancing electrons and molar weights and the periodic table and shit but I just stopped going to school.
   
   Never did any real bench chemistry in school. They don't teach you shit, when I read chemistry textbooks https://library.sciencemadness.org/library/books/Brent_GBC.pdf that CHILDREN from the 70s used to read and i'm trying to use the methods to cook drugs it's pretty funny how bad modern education is. THEY DOn"T TEACH THESE ZOOMERS NOTHING but actually that's not true, the Zoomer generation of chemists is building upon 20+ years of clandestine underground chemistry research starting from the USENET days and although most of it was done by methcooks and phreakz nowadays that has turned into being able to produce any chemical or compound in a home lab and if you DON"T want to break the law and are a zoomer with a chemistry textbook from the 70's and an interest in science in 2024 suddenly the world is your oyster and THEY ARE MAKING THE BEST OF IT AND COMING UP WITH REVOLUTIONARY CHEMISTRY IMPROVEMENTS I think they will cure cancer in our lifetimes unless we die from cancer first, they have all the tools.
   
   The drugs of the future will be some sci-fi shit with no comedown and biohacking
   
   
   Making cinnamon aldehydes (flavorings) from STYRENE is actually fucking genius and YES THIS METHOD COULD BE ADOPTED TO MAKE DRUGS FROM WASTE MATERIAL (which is already done for industrial illegal drugs, search 'catechol MDMA')
   
   

   Allylbenzene is a relevant precursor for the synthesis of amphetamines, just like safrole is one of the main precursors for the synthesis of MDMA. Aquiring Allylbenzene can be somewhat tricky, as it is a somewhat watched chemical because many chemical supply companies know what it can be used for. Unlike safrole, allylbenzene does not occur in large amounts in nature, but a chemical relative which does is cinnamaldehyde (3-phenyl-propenal).
   
   The essential oil of cinnamon bark consists of about 90% cinnamaldehyde, and this can be isolated by vacuum distillation (bp 250°C at ordinary pressure). Do not use the oil of cinnamon leaves, because that consists chiefly of eugenol (70-90%). Cinnamaldehyde can also be had by the reduction of cinnamic acid or the oxidation of cinnamyl alcohol.
   
   If we could somehow reduce the aldehyde group of cinnamaldehyde to a methyl group, propenylbenzene would be formed. This cannot be done directly though, but it is possible to condense cinnamaldehyde with para-toluenesulfonylhydrazide to form cinnamaldehyde tosylhydrazone, which in turn can be reduced by sodium borohydride or sodium cyanoborohydride to allylbenzene1. These procedure is described below.
   
   A similar procedure, using bis(benzoyloxy)borane (made in situ from benzoic acid and BH3·THF) as the reducing agent2, boasts a 95% yield (85% isolated) of allylbenzene from cinnamaldehyde tosylhydrazone.

9. 2024-07-21 at 6:10 AM UTC

   #29
   

   The Magus Yung Blood
   Drugs can be formulated from alchemies of meaning and your brain does this endogenously. You can learn to do this with relative ease, if you think creatively about an occult subject with the intent for consumption of media. Any vice is suitable for you to purpose a meaning that can become for your consciousness something of truth for its working to change in a subtle way, or a grander way if you achieve profundity in this attempt.
10. 2024-07-21 at 11:01 AM UTC

    #30
    

    the man who put it in my hood Black Hole [miraculously counterclaim my golf]
    These zoomers are rediscovering oldje abandoned big pharma patents from liek 1940 and making some killer grey market shit that you aren't gonna see on your faggot clearnet darknet chinese suppliers for 5 years and by the time it's banned they will have invented 500 new ones you never heard of
    
11. 2024-07-22 at 10:56 PM UTC

    #31
    Lanny Lanny African Astronaut

    Originally posted by the man who put it in my hood These zoomers are rediscovering oldje abandoned big pharma patents from liek 1940 and making some killer grey market shit that you aren't gonna see on your faggot clearnet darknet chinese suppliers for 5 years and by the time it's banned they will have invented 500 new ones you never heard of

    
    I dont even know how to get on the fucking darknet. all I hear is TOR onion but HOW?
    
    I dont plan on buying shit just researching shit you can't do on the rugular search engine. forget deep searching Conspiracy related shit
12. 2024-07-22 at 11:12 PM UTC

    #32
    

    the man who put it in my hood Black Hole [miraculously counterclaim my golf]
    you download a client, press "connect" and then type the web address in the bowser
    
    
    
    

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13. 2024-07-22 at 11:13 PM UTC

    #33
    

    Bradley Florida Man [my infernally top-secret etiology]
    OP needs to try sucking cock.
14. 2024-07-22 at 11:16 PM UTC

    #34
    Lanny Lanny African Astronaut

    Originally posted by the man who put it in my hood you download a client, press "connect" and then type the web address in the bowser

    
    Never worked that simple for me Nig. there is some tweaking on the settings you need to do.
15. 2024-07-23 at 12:07 AM UTC

    #35
    

    the man who put it in my hood Black Hole [miraculously counterclaim my golf]
    do you have the bowser?
    
    https://www.torproject.org/
16. 2024-07-23 at 3:58 AM UTC

    #36
    Lanny Lanny African Astronaut

    Originally posted by the man who put it in my hood do you have the bowser?
    
    https://www.torproject.org/

    
    Yeah why. how do you set up the settings to have it actually find shit
17. 2024-07-23 at 6:20 PM UTC

    #37
    

    the man who put it in my hood Black Hole [miraculously counterclaim my golf]
    Find what? You have to be connected to the TOR network to view onion links. Just press the connect button and you can start putting links in it just like a normal internet bowser
    
    heres some links to get your started on the dark web
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