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how to make crystalized dmt?
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2017-05-12 at 5:42 PM UTCa kilo of mimosa hostilis, treated properly, will get you lots of dmt.
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2017-05-12 at 5:46 PM UTC
Originally posted by snab_snib a kilo of mimosa hostilis, treated properly, will get you lots of dmt.
100 g would be theory. That is quite a bit of the compound but from what i hear large scale extraction doesnt yeild as much for whatever reason. Then again if the procedure were performed perfectly (i.e. good form, lab setup and chems) there is a huge difference.
But i digress. Much of that very well may end up being nmt anyway. Not nessicarily a bad thing if you dont mind an impure trip. -
2017-05-12 at 8:17 PM UTCPiss on a Dream Cast.
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2017-05-13 at 10:03 AM UTC
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2017-05-13 at 3:47 PM UTC
Originally posted by AltarEgo 100 g would be theory. That is quite a bit of the compound but from what i hear large scale extraction doesnt yeild as much for whatever reason. Then again if the procedure were performed perfectly (i.e. good form, lab setup and chems) there is a huge difference.
But i digress. Much of that very well may end up being nmt anyway. Not nessicarily a bad thing if you dont mind an impure trip.
you're not getting it in one pull, and you're going to want to precipitate and then mix the powder back into the wax. you're not getting 10% yield in powder or shards. it has to be wax. -
2017-05-13 at 3:53 PM UTCWhat the fuck are you talking about wax?
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2017-05-13 at 4:30 PM UTCTo actually make (synthesize) DMT would be a waste of time when extraction is so much easier. You could go the classic L-tryptophan > tryptamine > DMT route, though. L-tryptophan is a dietary supplement, so it's easy as fuck to get.
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2017-05-13 at 4:41 PM UTC
Originally posted by 1337 To actually make (synthesize) DMT would be a waste of time when extraction is so much easier. You could go the classic L-tryptophan > tryptamine > DMT route, though. L-tryptophan is a dietary supplement, so it's easy as fuck to get.
No you can start from indole and react with oxalyl chloride and yield an ounce or kilogram with not much more effort for scaling up, through in the past 20 years indole has been increasingly more difficult to obtain because I believe you can also make all the 2C's with it, as well as Syncans. But I predict that once weed becomes legalized federally in the USA and syncans become more well controlled than things like Indole will be easier to get which means clandestine producers will be able to produce DMT again. It's one of those drugs that has eluded the clandestine community in large amounts for a very long time.
Thats why so much effort was put into the tryptophan route in the 90's and early 2000's because of the indole situation, and now I consider it like beating a dead horse as the only way it's ever gonna worth it to make DMT that way is some kind of chemical engineering innovation.
Even Leonard Pickard, Nick Sand and several others in that community (the same one as Sasha Shulgin) spent lots of money and time researching DMT synthesis because demand was VERY high among the psychedelic community but no amount of Mimosa Root bark imported and extracted would ever meet that demand. The research was abandoned and forgotten mostly.
There are some efforts now being put towards it all in 2017.
Even on the darknet the only DMT I have seen is made from people extracting it in small batches. -
2017-05-13 at 4:54 PM UTCDo you think a person asking on this forum how to make DMT is going to go through the trouble of getting restricted precursors? If he's planning on becoming a kingpin like Pickard, et al., with a professional lab, sources, and know-how, that's one thing, but this guy is a noob.
Your chemistry posts intrigue me. Just because you read on the internet how you can mix two chemicals and get something you desire doesn't mean that it's feasible for a typical person who just wants to get high. Like how you think you can be the next Nick Sand because you have a source for wheat with ergot growing on it. It takes a lot more than reading a lab procedure on the internet to turn contaminated wheat into tabs of LSD. -
2017-05-13 at 5:09 PM UTC
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2017-05-13 at 5:09 PM UTC
Originally posted by 1337 Your chemistry posts intrigue me. Just because you read on the internet how you can mix two chemicals and get something you desire doesn't mean that it's feasible for a typical person who just wants to get high. Like how you think you can be the next Nick Sand because you have a source for wheat with ergot growing on it. It takes a lot more than reading a lab procedure on the internet to turn contaminated wheat into tabs of LSD.
It wouldn't be very far fetched for an amateur chemist to get or make indole, same with oxalyl chloride, the only reason this hasn't caught on in the mainstream is the same reason you don't have every tweeker making p2p from benazaldehyde/MEK and MDMA without safrole. The technology exists but the only people who care about this stuff aren't gangster drug manufacturers or psychedelic gurus. Right now these people are mostly drug nerds and people in academia, there are LOTS of papers covering alternate reductions/synthesis to all kinds of drugs and this has been researched extensively on drug synth forums for the past 20 years as the future to the synthesis of all kinds of restricted drugs.
Even when it comes to LSD, yeah okay LSA and ergot are extremely difficult to obtain but because of that Paspalli culturing and alternate routes have gained more interest. There is even a theoretical route starting from Kentucky 31 tall fescue infected with endophyte to yield ergoline alkaloids in the grass which is simply mowed, collected, defatted and extracted to collect the alkaloids. Casey Hardison was also able to perform the reduction using entirely unwatched peptide coupling reagents.
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2017-05-13 at 5:10 PM UTCbulk mushrooms would be much more profitable. ~$100 of supplies and a half lb of product
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2017-05-13 at 7:02 PM UTC
Originally posted by greenplastic bulk mushrooms would be much more profitable. ~$100 of supplies and a half lb of product
I read a question and answer on Shulgin's website a long time ago about getting different novel tryptamines from psilocybin-producing mushrooms by adding different ingredients to the growth medium. Naturally, the mushrooms convert l-tryptophan into DMT as an intermediary step to making psilocin via oxidation*. I'm not sure what he spoke of adding to the medium
*
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2017-05-13 at 7:06 PM UTC
Originally posted by 1337 I read a question and answer on Shulgin's website a long time ago about getting different novel tryptamines from psilocybin-producing mushrooms by adding different ingredients to the growth medium. Naturally, the mushrooms convert l-tryptophan into DMT as an intermediary step to making psilocin via oxidation*. I'm not sure what he spoke of adding to the medium
*
I wonder if genetic modification would help the process along somehow, like for example if a certain reaction uses glucose and you modify the organism to increase the amount of glucose during that step to increase yield. -
2017-05-13 at 7:06 PM UTC
Originally posted by SCronaldo_J_Trump It wouldn't be very far fetched for an amateur chemist to get or make indole, same with oxalyl chloride, the only reason this hasn't caught on in the mainstream is the same reason you don't have every tweeker making p2p from benazaldehyde/MEK and MDMA without safrole. The technology exists but the only people who care about this stuff aren't gangster drug manufacturers or psychedelic gurus. Right now these people are mostly drug nerds and people in academia, there are LOTS of papers covering alternate reductions/synthesis to all kinds of drugs and this has been researched extensively on drug synth forums for the past 20 years as the future to the synthesis of all kinds of restricted drugs.
Even when it comes to LSD, yeah okay LSA and ergot are extremely difficult to obtain but because of that Paspalli culturing and alternate routes have gained more interest. There is even a theoretical route starting from Kentucky 31 tall fescue infected with endophyte to yield ergoline alkaloids in the grass which is simply mowed, collected, defatted and extracted to collect the alkaloids. Casey Hardison was also able to perform the reduction using entirely unwatched peptide coupling reagents.
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2017-05-13 at 7:14 PM UTCErgot alkaloids would never be discovered without crude experimentation by Hoffman, Stoll and others in the early days. Their work led to many innovations in the commercial production of ergot alkaloids and this paved the way for future scientists to build upon that work to end up with what is now top secret multibillion dollar patents, processes and methods for the production of ergot alkaloids, LSD and related compounds.
Clandestine efforts are not much different. -
2017-05-13 at 7:16 PM UTC
Originally posted by SCronaldo_J_Trump I wonder if genetic modification would help the process along somehow, like for example if a certain reaction uses glucose and you modify the organism to increase the amount of glucose during that step to increase yield.
There is very little residual DMT in psychedelic mushrooms, so I imagine there is an electro-chemical reason for not keeping DMT around in the tissues (I should have paid more attention in p-chem). It would probably be easier just to convert the psilocybin back into DMT rather than artificially selecting or modifying mushrooms to change the amount of intermediate DMT kept around.
Edit: I wish Gun Lover was still around. He's the biggest pharmacology nerd I've ever met.
