teh retraded thred herppppp slober fuk glum editshin

1. 2017-02-20 at 5:38 AM UTC

   #961
   cerakote African Astronaut

   Originally posted by reject So you'd never do acid or shrooms? Or alcohol? Man you're a weakfag

   
   i guess i forgot to include eating/drinking
   
   ive been drunk before and ive tried acid many a time
2. 2017-02-20 at 5:39 AM UTC

   #962
   

   Sophie Pedophile Tech Support
   It's not the histamine release that makes you high Bling Blongerol, normally opioids bind to the micro-opioid receptor and that is what makes you high. Codeenz don't readily bind to the micro-opioid receptor they need to be converted to morphine and codeine-6-glucuronide to become active.
3. 2017-02-20 at 5:40 AM UTC

   #963
   The Self Taught Man Black Hole

   Originally posted by Sophie It's not the histamine release that makes you high Bling Blongerol, normally opioids bind to the micro-opioid receptor and that is what makes you high. Codeenz don't readily bind to the micro-opioid receptor they need to be converted to morphine and codeine-6-glucuronide to become active.

   
   I believe you are referring to the mu-opioid receptor
4. 2017-02-20 at 5:42 AM UTC

   #964
   

   Lanny Bird of Courage
   Yeah, I always thought it was "mu" like the letter, not micro, but I don't really know. Honestly I've only ever seen it written so I have no idea how you're supposed to say it.
5. 2017-02-20 at 5:43 AM UTC

   #965
   

   Sophie Pedophile Tech Support

   Originally posted by Hash Slinging Slasher I believe you are referring to the mu-opioid receptor

   
   That's just another way of saying micro. In fact it's a conflagration of the term MOR and u for micro.
6. 2017-02-20 at 5:45 AM UTC

   #966
   

   Sophie Pedophile Tech Support
   Also, you have delta-opioid receptors too, so trust me it's a Greek betabet thing.
7. 2017-02-20 at 5:47 AM UTC

   #967
   

   aldra JIDF Controlled Opposition
   have you forgotten who you're talking to
8. 2017-02-20 at 5:47 AM UTC

   #968
   The Self Taught Man Black Hole

   Originally posted by aldra

   
   http://www.cc.com/video-clips/c8etub/reno-911--nudist-future-shock
9. 2017-02-20 at 5:55 AM UTC

   #969
   The Self Taught Man Black Hole

   Originally posted by Sophie That's just another way of saying micro. In fact it's a conflagration of the term MOR and u for micro.

   
   Ah, gotcha. Never heard that before
   
   
   

   Originally posted by Sophie Also, you have delta-opioid receptors too, so trust me it's a Greek betabet thing.

   
   Yeah but delta opioid receptors are no fun
10. 2017-02-20 at 6:10 AM UTC

    #970
    

    bling bling Dark Matter
    
    The following users say it would be alright if the author of this post didn't die in a fire!

    • aldra
11. 2017-02-20 at 6:11 AM UTC

    #971
    

    bling bling Dark Matter
    Codeine IV
    30mg/mL (1mL ampoule)
    Sandoz, Canada
12. 2017-02-20 at 6:22 AM UTC

    #972
    

    Sophie Pedophile Tech Support

    Originally posted by bling bling Codeine IV
    30mg/mL (1mL ampoule)
    Sandoz, Canada

    
    The point is, the trade off is not worth it. You will get all the shittyness of a histamine reaction while it still takes a long time to start working since it needs to be metabolized to be active.
    
    In general, people IV shit, because it works instantly it won't in the case of codeine.
13. 2017-02-20 at 6:33 AM UTC

    #973
    

    bling bling Dark Matter
    
14. 2017-02-20 at 6:41 AM UTC

    #974
    

    Lanny Bird of Courage

    Originally posted by Sophie Also, you have delta-opioid receptors too, so trust me it's a Greek betabet thing.

    
    But ∂ isn't a metric prefix the way µ is, which would seem to suggest the µ in "μ-opioid receptor" just refers to the greek letter rather than meaning "micro".
15. 2017-02-20 at 6:42 AM UTC

    #975
    

    aldra JIDF Controlled Opposition

    Originally posted by bling bling

    
    
    lolwtf
    
    why does this even exist
    
    aside from it being useless since codeine isn't active until it's metabolised in the liver, IV/IM can actually cause pulmonary oedema
    The following users say it would be alright if the author of this post didn't die in a fire!

    • Sophie
16. 2017-02-20 at 6:51 AM UTC

    #976
    The Self Taught Man Black Hole
    yee high again, off to fuck some anime waifuz
17. 2017-02-20 at 7:01 AM UTC

    #977
    

    Sophie Pedophile Tech Support

    Originally posted by Lanny But ∂ isn't a metric prefix the way µ is, which would seem to suggest the µ in "μ-opioid receptor" just refers to the greek letter rather than meaning "micro".

    
    Well shit nigger. Don't ask me, ask a pharmacist, it's just the way it is. Or ask my sister, she almost has her masters in biopharmaceutical sciences you know. Matter of fact, i will ask her and get back to you.
18. 2017-02-20 at 7:02 AM UTC

    #978
    

    bling bling Dark Matter
    ask he can u iv dhc
19. 2017-02-20 at 7:30 AM UTC

    #979
    

    bling bling Dark Matter
    plz
20. 2017-02-20 at 7:30 AM UTC

    #980
    

    bling bling Dark Matter
    plx