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Posts by frumbob ππ¦ππ―π·π¦
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2019-07-08 at 4:08 AM UTC in How many times does somebody have to be raped before it begins to be their fault?
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2019-07-08 at 4:04 AM UTC in How many times does somebody have to be raped before it begins to be their fault?wifebeating can be justifiable. women arent strong physically so they excel at psychological abuse, and then present themselves at victims when a man responds to this abuse physically. its basically gaslighting since everything the woman did to abuse the man can be denied as it left no visible mark. also making women suffer is sexy
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2019-07-08 at 3:34 AM UTC in How many times does somebody have to be raped before it begins to be their fault?
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2019-07-08 at 2:52 AM UTC in My wife is pregnant
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2019-07-08 at 2:51 AM UTC in My wife is pregnantmy dad cant stop hallucinating race wars and kike conspiracies
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2019-07-08 at 2:48 AM UTC in What are you doing to prepare for the coming race war?schizophrenia
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2019-07-08 at 2:44 AM UTC in My wife is pregnantyou have schizophrenia
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2019-07-08 at 2:42 AM UTC in fish never get dirtywet
/wet/
adjective
1.
covered or saturated with water or another liquid
air is not a liquid -
2019-07-08 at 2:40 AM UTC in fish never get dirty
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2019-07-08 at 1:23 AM UTC in The Retarded Thread: Malice Metro Edition
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2019-07-07 at 11:20 PM UTC in fish never get dirty
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2019-07-07 at 11:04 PM UTC in fish never get dirty
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2019-07-07 at 10:49 PM UTC in fish never get dirtytheyre always getting cleaned by water
lucky ass mfs -
2019-07-07 at 10:36 PM UTC in Diet drugs
Originally posted by DietPiano Bacon is way too expensive for what it is. I've had it like 12 times in 4 years, although I do have some now (first pack I've ever bought). It's processed and bad for you and doesn't really taste better than OK.
i also keep tallies of every time i've eaten bacon and order artisan chewing gum online -
2019-07-07 at 2:29 PM UTC in anyone here ever eat a fuckload of immodium to get high
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2019-07-07 at 8:36 AM UTC in What genetic information is in girls/womens eggs?you stupid son of a bitch
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2019-07-07 at 8:23 AM UTC in You will always be my bbdidnt listen
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2019-07-07 at 8:17 AM UTC in anyone here ever eat a fuckload of immodium to get high
Originally posted by JΟ icebox Some bees or whatever the fuck they called themselves on the hive supposedly figured out some way of coating it in polysorbate-80 and shooting it with mannitol that supposedly got you high
the polysorbate 80 and mannitol method are separate i'm pretty sure. both would make it readily pass the BBB so you only need to do one or the other
i would think the polysorbate 80 method is far more difficult since it has to form a molecular bond with the loperamide, not just mixing them together -
2019-07-07 at 8:10 AM UTC in You will always be my bbi love mal :(
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2019-07-07 at 8:06 AM UTC in anyone here ever eat a fuckload of immodium to get high
Originally posted by gadzooks It doesn't. That's the whole conundrum.
If you can somehow get it directly into your brain (like.,. Via a hole in the top of your skull.,. Not even remotely practical in the real world).,. Then you're all set (in theory at least).
But in the real world, immodium will do nothing but constipate.
it does cross the blood brain barrier. the bio-availability of loperamide is 0.3%, only a percent of that 0.3% is able to make it past the BBB, and then p-glycoprotein in the brain pushes it back out, so you end up with very minute quantities able to stay in the brain, but since once in the brain it has around the potency of fentanyl, that is not a huge issue, as long as you take like 200mg+, and use p-glycoprotein inhibitors/ cyp3a liver enzyme inducers. im scratching my skin off rn and was almost nodding for 20 minutes so it definitely works, but i dont really consider it to be a worthwhile buzz
i've also heard of someone injecting mannitol, which opens the BBB for a 10 minute time frame, and then injecting lope, and having it hit with a full effect