SPANISH OPPOSITIONto the Aztecs' worship of pagan deities with the sacramental aid of mushrooms was strong. Although the Spanish conquerors of Mexico hated and attacked the religious use of all hallucinogens - peyote, ololiuqui, toloache, and others - teonanocatl was the target of special wrath. Their religious fanaticism was drawn especially toward this despised and feared form of plant life that, through its vision-giving powers, held the Indian in awe, allowing him to commune directly with his gods. The new religion, Christianity, had nothing so attractive to offer him. Trying to stamp out the use of the mushrooms, the Spaniards succeeded only in driving the custom into the hinterlands, where it persists today. Not only did it persist, but the ritual adopted many Christian aspects, and the modern ritual is a pagan-Christian blend.
OPPOSITION TO THE USE OF PEYOTEby the Aztecs was strong among the Spanish conquerors. One early Spanish church document likened the eating of peyote to cannibalism. Upset by the religious hold that peyote had on the Indians, the Spanish tried, with great vigor but little success, to stamp out its use. By 1720, the eating of peyote was prohibited throughout Mexico. But despite four centuries of civil and ecclesiastical persecution, the use and importance of peyote have spread beyond its early limited confines. Today it is so strongly anchored in native lore that even Christianized Indians believe that a patron saint—El Santo Niño de Peyotl—walks on the hills where peyote grows. There is continuing opposition in certain religious organizations in the United States to the Indians' use of peyote as a ceremonial sacrament. Nevertheless, the federal government has never seriously questioned or interfered with the practice since it is essentially a religious one. Those tribes living far from sources of peyote—some as far north as Canada—can legally import mescal buttons by mail. Despite constitutional guarantees separating church and state, however, a few states have enforced repressive laws against even the religious use of peyote