2020-01-06 at 3:22 AM UTC
Men
Immodium has caused exponentially more heart attack deaths than all other opiates combined and killed our spiritual leader
It needs to be banned NOW!
Immodium should be pulled off the shelves immediately, and to replace the OTC anti-diarrhea medicine gap should be other, much more effective anti-diarrheals that are infinitely better for your heart like oxycodone and morphines
Sign my online petition
2020-01-06 at 3:48 AM UTC
Nah. Worked well here, will continue God's work well out there. Long live Immodium.
2020-01-06 at 8:48 AM UTC
Says guy who supports vape ban
2020-01-06 at 12:12 PM UTC
Im pretty depressed my girlfriend says she loves me but I suspect otherwise I think I'm gonna buy a box of Imodium today and see what it's like
2020-01-06 at 1:08 PM UTC
ill mix it with belladonna
2020-01-06 at 2:18 PM UTC
-SpectraL
coward
[the spuriously bluish-lilac bushman]
Concurrent administration of P-glycoprotein inhibitors such as quinidine potentially allows loperamide to cross the blood–brain barrier and produce central morphine-like effects. Loperamide taken with quinidine was found to produce respiratory depression, indicative of central opioid action.
Loperamide has typically been deemed to have a relatively low risk of misuse.[62] In 2012, no reports of loperamide abuse were made.[63] In 2015, however, case reports of extremely high-dose loperamide use were published.[64][65] Primary intent of users has been to manage symptoms of opioid withdrawal such as diarrhea, although a small portion derive psychoactive effects at these higher doses.[66] At these higher doses central nervous system penetrance occurs and long term use may lead to tolerance, dependence, and withdrawal on abrupt cessation.[66] Dubbing it "the poor man's methadone", clinicians warned that increased restrictions on the availability of prescription opioids passed in response to the opioid epidemic were prompting recreational users to turn to loperamide as an over-the-counter treatment for withdrawal symptoms.[67] The FDA responded to these warnings by calling on drug manufacturers to voluntarily limit the availability of loperamide for public-safety reasons, in an analogous manner to restrictions put on the sales of pseudoephedrine, to be sold only in limited amounts.[68][69] Since 2015, several reports of sometimes-fatal cardiotoxicity due to high-dose loperamide abuse have been published.[70][71]
