2019-08-04 at 12:36 PM UTC
Jealous of his alcoholism, mental illness, and destitution? No thanks.
2019-08-04 at 1:56 PM UTC
aldra
JIDF Controlled Opposition
yeah don't replace with benzos, they'll be a lot easier to manage than alcohol but getting off them will be even worse. and you'll black out a lot more.
taper if you're serious about it
2019-08-04 at 2:04 PM UTC
Cold Turkey or you ain't serious.
2019-08-04 at 2:31 PM UTC
aldra
JIDF Controlled Opposition
cold turkey with gabaergics can actually kill you
2019-08-04 at 2:43 PM UTC
i would just like to say im alcohol free for 130+ days.
thank you.
The following users say it would be alright if the author of this
post didn't die in a fire!
2019-08-04 at 2:52 PM UTC
-SpectraL
coward
[the spuriously bluish-lilac bushman]
Gamma aminobutyric acid (GABA) represents the major inhibitory neurotransmitter of the central nervous system. Ethanol as well as benzodiazepines (BDZs) and some anticonvulsant drugs directly affect GABAA receptors inducing similar anxiolytic, sedativehypnotic, and anticonvulsant effects. Since BDZs have proven their efficacy in ameliorating symptoms and in decreasing the risk of seizures and delirium tremens, they are the drugs of choice for the treatment of alcohol withdrawal syndrome (AWS). However, due to their addictive potential and lack of safety when combined with alcohol, BDZs are usually not recommended for the maintenance of alcohol abstinence. Other GABA-ergic medications represent potentially promising drugs useful in the treatment of AWS and in maintaining alcohol abstinence. Indeed, available studies have demonstrated that clomethiazole, gabapentin and gamma hydroxybutyrate (GHB) present a similar efficacy to BDZs in suppressing AWS. In addition, current evidence also indicates that gabapentin and GHB do not have significant interactions with ethanol that render them safe to use in maintaining alcohol abstinence. Moreover, gabapentin and valproic acid may be beneficial in maintaining alcohol abstinence in alcoholics with psychiatric co-morbidity. Pregabalin, neurosteroids, tiagabine, and vigabatrin need further clinical evidence of efficacy, safety and tolerability. Thus, given the importance of GABA-ergic mechanisms in the development and maintenance of alcohol dependence, and the very interesting results currently achieved, more research on GABAergic agents is warranted.
2019-08-04 at 3:11 PM UTC
god I hate you kro z
hows your fucking cat?