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Scientists in Kentucky sequence Mexican salamander genome
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2019-01-24 at 10:45 PM UTC
Scientists have pieced together the complete genome of a salamander with unparalleled regeneration abilities in a breakthrough that could have huge implications for human limb replacement.
The axolotl – a Mexican salamander known as well for its perpetually-smiley appearance as for its ability to sprout new limbs – is remarkable in its ability to regrow just about any damaged body part.
In a groundbreaking study, researchers in the US say they’ve assembled the axolotl genome, putting us closer to finally understanding how the amphibians are able to do this.
‘It’s hard to find a body part they can’t regenerate: the limbs, the tail, the spinal cord, the eye, and in some species, the lens, even half of their brain has been shown to regenerate,’ said Randal Voss, a professor in the University of Kentucky Spinal Cord and Brain Injury Research Center.
Sequencing a large genome is no easy task, and has so far stood in the way of unlocking the axolotl’s secrets.
But thanks to recent efforts, scientists have been inching closer and closer to assembling it in the correct order.
In the new study, the University of Kentucky team adapted an approach known as linkage mapping to quickly put the axolotl genome in order.
According to the researchers, this is the first time a genome so large has been assembled.
https://www.dailymail.co.uk/sciencetech/article-6628785/Incredible-regeneration-powers-Mexican-axolotl-soon-help-humans-regrow-LIMBS.html
Coooll -
2019-01-24 at 11 PM UTCZok is a nigger
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2019-01-24 at 11:02 PM UTC
According to the researchers, this is the first time a genome so large has been assembled.
Haven't we had human whole genome sequencing for like a decade? -
2019-01-24 at 11:06 PM UTC
Originally posted by omn5;pvl human genome has been sequenced for 20 years and we still know almost nothing about complex traits. civilization will collapse long before we figure out how to use this for regenerative medicine
Yeah but, civilization and the military industrial complex are two different things. Those nuclear bomb resistant bunkers and actually whole cities hidden underground will remain, and the researchers down there, doing the best, most advanced research, will continue researching. What we're told about in the mainstream is light-years behind what the military industrial complex has in terms of technological sophistication. Civilization can collapse, they may even want it to, but it won't affect them. That's why the NSA allowed 9/11 to happen. If you aren't chosen, you don't matter. -
2019-01-24 at 11:09 PM UTCdoubtful
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2019-01-24 at 11:10 PM UTC
As of 2017 there were no complete genomes for any mammals, including humans. Between 4% to 9% of the human genome, mostly satellite DNA, had not been sequenced.[8]
https://en.wikipedia.org/wiki/Whole_genome_sequencing"Psst, the human genome was never completely sequenced". STAT. 2017-06-20. Archived from the original on 2017-10-23. Retrieved 2017-10-23.
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2019-01-24 at 11:11 PM UTCZok is a nigger
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2019-01-24 at 11:16 PM UTC
Originally posted by omn5;pvl wikipedia is not a source, university has taught me this
That's why I also quoted the citation.
The feat made headlines around the world: “Scientists Say Human Genome is Complete,” the New York Times announced in 2003. “The Human Genome,” the journals Science and Nature said in identical ta-dah cover lines unveiling the historic achievement.
There was one little problem.
“As a matter of truth in advertising, the ‘finished’ sequence isn’t finished,” said Eric Lander, who led the lab at the Whitehead Institute that deciphered more of the genome for the government-funded Human Genome Project than any other. “I always say ‘finished’ is a term of art.”
“It’s very fair to say the human genome was never fully sequenced,” Craig Venter, another genomics luminary, told STAT.
“The human genome has not been completely sequenced and neither has any other mammalian genome as far as I’m aware,” said Harvard Medical School bioengineer George Church, who made key early advances in sequencing technology.
Related: A baby with a disease gene or no baby at all: Genetic testing of embryos creates an ethical morass
What insiders know, however, is not well-understood by the rest of us, who take for granted that each A, T, C, and G that makes up the DNA of all 23 pairs of human chromosomes has been completely worked out. When scientists finished the first draft of the human genome, in 2001, and again when they had the final version in 2003, no one lied, exactly. FAQs from the National Institutes of Health refer to the sequence’s “essential completion,” and to the question, “Is the human genome completely sequenced?” they answer, “Yes,” with the caveat — that it’s “as complete as it can be” given available technology.
Perhaps nobody paid much attention because the missing sequences didn’t seem to matter. But now it appears they may play a role in conditions such as cancer and autism.
“A lot of people in the 1980s and 1990s [when the Human Genome Project was getting started] thought of these regions as nonfunctional,” said Karen Miga, a molecular biologist at the University of California, Santa Cruz. “But that’s no longer the case.” Some of them, called satellite regions, misbehave in some forms of cancer, she said, “so something is going on in these regions that’s important.”
Rest of article: https://www.statnews.com/2017/06/20/human-genome-not-fully-sequenced/ -
2019-01-24 at 11:18 PM UTCZok is a nigger
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2019-01-24 at 11:21 PM UTC
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2019-01-24 at 11:27 PM UTCNo biology majors in this thread yet.
How do I become a geneticist?
If you are interested in becoming a geneticist, regardless of your eventual career path, you should start by taking plenty of math and science courses in high school, especially biology and chemistry. In college, biology, chemistry, and biochemistry are popular majors for those interested in genetics careers. Larger institutions may offer more specialized majors such as genetics or molecular biology. Again, you will need to take plenty of math and science classes, and do well in these classes. With your undergraduate science degree, many paths in genetics are open to you!
https://www.ashg.org/education/careers.shtml -
2019-01-25 at 1:48 PM UTC
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2019-01-25 at 2 PM UTCSoyboy IV: The Flower of Death and The Crystal of Life African Astronaut [the oppositely able-bodied hop-step-and-jump]
I hate when journalists say stupid shit like DNA research will allow humans to regrow limbs.
Journalism is such a sleazy profession I can't even believe it.
Originally posted by Lanny Haven't we had human whole genome sequencing for like a decade?
Axolotyl's have freakishly large genomes for basically no good reason. -
2019-01-25 at 2:49 PM UTC"Axolotyl" Sounds like something you get at Walgreens.
