High blood pressure Higher levels of LDL cholesterol, which is widely considered "bad cholesterol," lower levels of HDL cholesterol, considered to be good cholesterol in moderation, and high levels of triglycerides Type II diabetes Coronary heart disease Stroke Gallbladder disease Osteoarthritis, a type of joint disease caused by breakdown of joint cartilage Sleep apnea and breathing problems Certain cancers (endometrial, breast, colon, kidney, gallbladder, liver) Low quality of life Mental illnesses such as clinical depression, anxiety, and others Body pains and difficulty with certain physical functions Generally, an increased risk of mortality compared to those with a healthy BMI