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Obbe

  1. #1
    Instigator Naturally Camouflaged [the staring tame crusher]
    The following users say it would be alright if the author of this post didn't die in a fire!
  2. #2
    Bradley Florida Man
    Woah It's like they're telling you it's radioactive
  3. #3
    the man who put it in my hood Black Hole [miraculously counterclaim my golf]
    lol @ obbe

    Microwave Chemistry Research

    Microwave Chemistry tips
    Microwave Chemistry FAQ
    Dariusz Bogdall's Microwave Syntheses
    Miscellaneous information on clays
    MW-chem: Preparation of alkyl azides from alkyl bromides
    MW-chem: Reductive amination with NaBH4
    MW-chem: Reduction of carbonyl compounds with NaBH4
    MW-chem: Nitroalkene preparation from benzaldehydes (PDF)
    MW-chem: Benzaldehydes from alcohols using MnO2/Silica (PDF)
    MW-chem: Preparation of beta-nitrostyrenes from styrenes
    MW-chem: An introductory overview from New Scientist by Gavin Whittaker
    MW-Chem: Catalytic Transfer Hydrogenation
    MW-Chem: Ethers from alcohols and alkyl halides
    MW-chem: Theoretical and mechanistical background (PDF)
    MW-chem: Organic Chemistry Review (PDF)
    MW-chem: Wolff-Kishner reduction of ketones to hydrocarbons (PDF)
    MW-chem: Oxidation of Alcohols to Ketones
    MW-chem: High-yielding Azidation of Primary and Secondary Tosylates
    MW-chem: Solvent-Free Nucleophilic Aromatic Substitution of Inactive Aryl Halides
    The oxidation of benzyl alcohol is representative of the general procedure employed. MnO2 'doped' silica (1.25 g, 5 mmol of MnO2 on silica gel, Selecto Scientific, 230-400 mesh with large surface area of 600m2/g) is thoroughly mixed with benzyl alcohol (108 mg, 1 mmol) and the material is placed in an alumina bath inside the MW oven and irradiated for 20 seconds. Upon completion of the reaction, monitored on TLC (hexane: AcOEt, 10:1), the product is extracted into methylene chloride, solvent removed and the residue passed through a bed of silica gel (4 cm) to afford exclusively benzaldehyde. The overoxidation to carboxylic acid is not observed. The same reaction could be completed in 2 h at a comparable temperature of 55 °C in an oil bath.
    CAUTION: In view of the hazards associated with an active oxidant due caution is recommended for its use at elevated temperatures; the localized temperature may be much higher than the bulk temperature of the bath in the microwave oven and we suggest that the oven be operated at a lower power and for a shorter duration of time.


    tl;dr microwaves save 10 steps, add 20 steps and save you 3 trips to the chemical store with only 1 bulk order purchase of raw material. IN an economy this is what's called supply chain management and innovative developmental research by technical sectors and industry.
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