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DIY Extended Release

  1. 2021-01-08 at 5:54 PM UTC
    #1
    aldra JIDF Controlled Opposition
    I'm looking to extend the duration of something that helps me sleep so I don't wake up at odd hours and have to redose. Dose is 10-50mg.

    A quick search landed me on the nootropics subreddit and they suggested either pressing it or combining it in a capsule with micellar casein as it gels up and takes time to digest, but I have no experience with it so I dunno.
  2. 2021-01-08 at 11:34 PM UTC
    #2
    RIPtotse victim of incest [my adversative decurved garbo]
    rape
  3. 2021-01-08 at 11:39 PM UTC
    #3
    The Self Taught Man Black Hole
    Grapefruit juice.
  4. 2021-01-08 at 11:43 PM UTC
    #4
    Sophie Pedophile Tech Support
    Is it a Benzo? It is my understanding that benzos are somewhat lipophilic which means they dissolve faster in lipids(fats) than in water. You could take some olive oil, break your benzo into pieces that will fit in a capsule, and combine them. So you have a capsule of olive oil with your benzo in it that you can take. It should slow down the rate of absorption. Kind of like how eating a stick of butter before you down a bunch of vodka will make it so you get drunk more gradually.
  5. 2021-01-08 at 11:45 PM UTC
    #5
    Sophie Pedophile Tech Support
    Originally posted by Donald Trump Grapefruit juice.

    Yes, also this. However Omeprazole and Pantoprazole inhibit the same enzyme much more effectively, plus you don't have to down a carton of juice right before bed.
  6. 2021-01-09 at 1:52 AM UTC
    #6
    jfakldjfkdaljfalkdfjlkad Tuskegee Airman
    You're going to end up blacking out and waking up to redose anyway.
  7. 2021-01-09 at 1:56 AM UTC
    #7
    aldra JIDF Controlled Opposition
    not a benzo, opioid RC that hits selective receptors (AP237)

    Originally posted by Donald Trump Grapefruit juice.

    works by inhibiting certain liver enzymes and I'm not sure which ones break this down



    Originally posted by Sophie Yes, also this. However Omeprazole and Pantoprazole inhibit the same enzyme much more effectively, plus you don't have to down a carton of juice right before bed.

    I can probably find some of that, won't it give me heartburn or some shit if I use it when I don't need it though?
  8. 2021-01-11 at 6:38 PM UTC
    #8
    Sophie Pedophile Tech Support
    Originally posted by aldra not a benzo, opioid RC that hits selective receptors (AP237)



    works by inhibiting certain liver enzymes and I'm not sure which ones break this down





    I can probably find some of that, won't it give me heartburn or some shit if I use it when I don't need it though?

    Omeprazole and pantoprazole? Not at all. And generally for opiates, the enzyme inhibition route works best. Unless the opioid in question has a very peculiar molecular structure,CYP2D6(the enzyme grapefruit juice and the 'prazoles' inhibit) will be the enzyme responsible for breaking it down. If it's a pro-drug like codeine, it will inhibit conversion to the psycho-active metabolite as well, so you might want to take that into account. I am pretty certain CYP2D6 will do the job just fine though since it's the main enzyme your body uses in hydroxylation, demethylation, and dealkylation. Which covers a whole slew of not just opioids but psychotropics in general, due to the way a lot of classes of them are built molecularly.
  9. 2021-01-12 at 5:34 AM UTC
    #9
    blaster master victim of incest
  10. 2021-01-12 at 5:38 AM UTC
    #10
    aldra JIDF Controlled Opposition
    I believe it. I'm not too worried because I don't shoot the stuff or do high doses, but it tastes awful and when I tried vaping a little it tasted like I'd just taken a deep breath from a bottle of pool cleaner
  11. 2021-01-12 at 9:45 AM UTC
    #11
    Sophie Pedophile Tech Support
    Originally posted by aldra I believe it. I'm not too worried because I don't shoot the stuff or do high doses, but it tastes awful and when I tried vaping a little it tasted like I'd just taken a deep breath from a bottle of pool cleaner

    Is it impurities or the substance itself that's caustic?
  12. 2021-01-12 at 11:13 AM UTC
    #12
    aldra JIDF Controlled Opposition
    I think it's the substance itself; heard people tried sniffing it and got instant massive nosebleeds
  13. 2021-01-12 at 1:22 PM UTC
    #13
    Jiggaboo_Johnson Black Hole
    Substances are a short term solution, the real solution is to fix your fucked up sleep cycle.

    The key to that is to maintain a proper sleep schedule go to bed at a reasonable hour at the same time every night...even if at first you lay there tossing and turning, eventually the cycle will kick in.

    melatonin is only to get you to sleep, not keep you asleep btw.
  14. 2021-01-12 at 1:33 PM UTC
    #14
    Sudo Black Hole [my hereto riemannian peach]
    melotonin fucked with my sleep. Try trazadone
  15. 2021-01-12 at 2:27 PM UTC
    #15
    aldra JIDF Controlled Opposition
    Originally posted by Jiggaboo_Johnson Substances are a short term solution, the real solution is to fix your fucked up sleep cycle.

    thanks dad
  16. 2021-01-12 at 4:11 PM UTC
    #16
    Jiggaboo_Johnson Black Hole
    Anytime, let me know if you need me to read you a bedtime story and tuck you in.
    The following users say it would be alright if the author of this post didn't die in a fire!
  17. 2021-01-12 at 11:43 PM UTC
    #17
    Jeff Houston
    Nutmeg
  18. 2021-01-12 at 11:46 PM UTC
    #18
    Jeff Houston
    Having fat and fiber in your tum tum will increase the time it takes your body to digest, thus..
  19. 2021-01-12 at 11:47 PM UTC
    #19
    Jeff Houston
    But seriously nutmeg will potentially potentate w.e u taking.
  20. 2021-01-12 at 11:48 PM UTC
    #20
    Jeff Houston
    Originally posted by Sudo melotonin fucked with my sleep. Try trazadone

    I've heard that trazadone can cause permanent impotence
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