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What happened to hydroxychloriquine?

  1. Technologist victim of incest
    Originally posted by Cathay Coof I haven't even repaid like with like.

    Repaid to who?
  2. Originally posted by MexicanMasterRace Nope. Studies. Medical reports.

    nein, nein, und nein.

    https://wattsupwiththat.com/2020/05/02/pseudo-science-behind-the-assault-on-hydroxychloroquine/
  3. You tear people down all the time, Soy. I mean it’s funny, but you do it. All the men here are catty little bitches.

    You talked shit on my banana pudding the other day like a bitter housewife.

    Also, sorry for posting off topic.
    The following users say it would be alright if the author of this post didn't die in a fire!
  4. Cathay Coof African Astronaut [the ariled affirmatory basinet]
    Originally posted by frala You tear people down all the time, Soy. I mean it’s funny, but you do it. All the men here are catty little bitches.

    You talked shit on my banana pudding the other day like a bitter housewife.

    Also, sorry for posting off topic.

    I don't even remember
  5. Originally posted by Cathay Coof No, it's a general observation. When grown men argue it's to get at the truth. It sounds and feels constructive. When you argue to tear people down.

    I'll have a discussion when there's something to discuss, fatty.
  6. -SpectraL coward [the spuriously bluish-lilac bushman]
    Originally posted by MexicanMasterRace Well he's obese and evidently has heart issues so he absolutely shouldn't be taking it.

    Thank you Doctor §m£ÂgØL.
  7. Speedy Parker Black Hole
    Originally posted by MexicanMasterRace Well he's obese and evidently has heart issues so he absolutely shouldn't be taking it.

    A> You are not a doctor.

    B> In relation to hydroxychloroquine doctors call those precautions not dangers.
  8. Yeah I'm not a doctor. I just know what doctors say. I'm not a doctor though! This is what the doctors say. And just so you know, I'm not a doctor at all. I heard this from doctors.
  9. Originally posted by MexicanMasterRace Yeah I'm not a doctor. I just know what doctors say. I'm not a doctor though! This is what the doctors say. And just so you know, I'm not a doctor at all. I heard this from doctors.

    and doctors are not researchers.

    they just hear those rumors from high priests of science.
  10. aldra JIDF Controlled Opposition
    Originally posted by Cathay Coof Why would they care about either one of those things?

    Look at the transfers of Federal Reserve wealth and Palestinian land that Trump/Kushner are presiding over. That is an incentive to keep Trump alive - at least for all the powerful interests I know of.

    Only people who have nothing else going on care about tweets or some drugs effectiveness.

    I have no idea what I was writing last night, I'll read it later
  11. -SpectraL coward [the spuriously bluish-lilac bushman]
    Originally posted by aldra I have no idea what I was writing last night, I'll read it later

    What if you left a big bag of money laying around last night, and now you wouldn't know where it is, or even that you had it!?
  12. -SpectraL coward [the spuriously bluish-lilac bushman]
    CoVID19__HCQTreatmentTable__4.26.20__Gov.Ducey


    The probabilities of clinical success using
    hydroxychloroquine with or without azithromycin +/-
    zinc against the novel betacoronavirus, SARS-CoV-2
    Physician
    Hospital
    Academic
    institution
    Location
    Date of data
    reporting

    Number of
    Patients seen

    Number
    treated with
    HCQ +-
    azithromyci
    n +/- zinc

    Improved Died Success
    defined as
    % of no
    mortality or
    probability
    of
    preventing
    death, P(D-
    )

    Qingdao, China
    3.16.20

    ? total unknown
    Use 100 at least
    since they said
    greater than a
    hundred were
    treated

    >100; 100
    will be
    used

    100
    assumed

    0 Up to
    100%
    may have
    improved

    Didier Raoult
    3.17.20

    26? 16? 15? ? ???

    Didier Raoult
    3.27.20

    80 79 63 1 98.7%

    [Didier Raoult
    4.7.20

    1,061 (may or not
    include the 80
    from 3.27.20
    paper)

    1,061 1,040 5 99.6%]

    Dr. Didier
    Raoult 4.20.20
    Million M,
    Lagier JC,
    Gautret P,
    Colson P,
    Fournier PE, et
    al at
    IHU_Mediterran
    ee Infection in
    Marseille,
    France

    1,411 1,061
    Rx
    HCQ+AZ

    973 8 (46
    with poor
    clinical
    outcome;
    47 with
    poor
    virologic
    al
    outcome
    91.7%
    .754%
    Risk of
    death in
    those tx
    with
    HCQ

    2

    Dr. Vladimir
    Zelenko 3.30.20
    Monroe, New
    York

    200 (65% of tests
    were + in his first
    200 patients)
    700 seen who
    were + or had
    clinical suspicion
    500 were not
    treated with HCQ
    Rx
    200 were high risk
    and treated with
    HCQ,
    Azithromycin and
    Zinc

    200 194;
    2
    intubated;
    4 with
    pneumoni
    a but not
    intubated,
    improving

    0 100%

    Dr. Vladimir
    Zelenko
    Monroe, New
    York
    4.12.20

    1,354 405 399
    (6
    hospitalize
    d of which
    4 were
    intubated
    and then
    extubated
    and 2
    deaths)

    2 2/405
    99.995%
    P(D-)
    0.005%
    risk of
    death

    Dr. Stephen
    Smith 4.2.20
    Smith Center for
    Infectious
    Diseases

    80
    Rx HCQ and
    azithro
    45% 29 % patients
    were prediabetic,
    47% diabetic and
    obese; average
    BMI of severely
    ill 30.7 obese;
    prediabetics are
    also at risk

    80 80,
    20 patients
    are
    intubated
    0!
    No
    deaths
    reported
    100%

    Dr. Zheng 4.2.20 11 11 0 ? ?
    Dr. Rob
    Richards

    15 14 14 0 93%

    Dr. Jeff Colyer,
    Overland Park,
    KS

    14 14 14 0 100%

    Dr. Daniel
    Hinthorn,
    Kansas City, KS

    21 21 21 0 100%

    Dr. Anthony
    Cardillo Mend

    Number = ? Rx HCQ +
    zinc

    All those
    treated

    0 100%

    3

    Urgent Care
    Sherman Oaks,
    Van Nuys,
    Burbank, CA
    4.6.20

    Unknown number
    of patients treated;
    Contact Mend
    Urgent Care for
    more info
    Sherman Oaks:
    818-646-2562 |
    Van Nuys: 818-
    646-4928 |
    Burbank: 818-
    843-8555

    He did not
    use
    azithromyci
    n
    Treated
    very sick
    patients all
    of whom
    greatly
    improved
    within 8-12
    hrs

    improved

    Dr. Marc Siegel
    New York, New
    York

    1 Rx HCQ 1 1 0 100%

    Seattle, WA
    group; NEJM
    publication

    ? 58% of
    COVID-19
    patients in
    ICU were
    diabetic
    with
    average
    BMI of 33,
    morbidly
    obese

    ? ? ?

    Dr. William
    Grace, NewYork
    ?
    Dr. Alex Lechin,
    Texas

    ?
    Dr. Joe Mather,
    Louisiana

    ?

    Dr. Zhong
    Nanshan,
    epidemiologist
    and
    pulmonologist,
    discovered
    SARS virus in
    2003, China
    ?

    Lee SH, Son H,
    Peck KR,
    Samsung
    Medical Center,

    211, HCQ 400mg
    po qd prophylactic
    treatment in long
    term care hospital
    211;
    189
    patients
    and 22
    211
    All viral
    tests were
    negative

    0 100%
    success0
    % death

    4

    Pusan National
    Univ. Hospital
    Republic of
    Korea
    4.20.20

    exposures careworker s

    Paolo Zanotto
    and President
    Bolsonaro,
    Brazil

    ? HCQ in use
    without significant
    debate or delay
    ?

    ?

    ?

    ?

    Dr
    s. A. Kapoor,
    U. Pandurangi,
    V. Arora et al
    India

    ? prophylactic use
    of HCQ in
    progress

    ?

    ?

    ?

    ?

    University of
    Minnesota

    Enrolling for a
    prophylactic study

    pending

    University of
    Queensland
    Centre for
    Clinical
    Research,
    Australia

    Chloroquine study
    in progress

    Univ of
    Washington
    -
    NYU Grossman
    School of
    Medicine

    2,000
    Enrolling now

    Columbia
    University
    ?

    University of
    Pennsylvania
    ?

    Rutgers

    ?
    Washington
    University in St.
    Louis, MO
    (WUSTL)
    Multicenter
    international
    trial called
    CROWN
    CORONATION
    or CROWN
    CORONA
    Dr. Michael S.
    Avidan principal
    investigator

    Hydroxychloroqui
    ne prophylaxis,
    An international,
    multi
    -site,
    randomized,
    double
    -blinded,
    Bayesian platform
    adaptive design
    clinical trial

    5

    Missouri,
    Australia,
    Canada, Ireland,
    South Africa,
    United
    Kingdom,
    Zambia
    Washington
    University in St.
    Louis, MO
    (WUSTL)
    Barnes-jedi
    Hospital
    Dr. Rachel M.
    Presti,
    Dr. Jane

    O’Halloran, co-
    leaders of the

    trial

    Chloroquine,
    HCQ, and AZ will
    be studied in those
    with novel
    betacoronavirus
    infection

    Asan Medical
    Center, Seoul,
    South Korea

    Enrolling
    comparison study
    Kaletra vs.
    hydroxychloroqui
    ne vs. placebo
    ?

    Chen Z, Hu J,
    Zhang Z et al,
    Renmin Hospital
    of Wuhan
    University,
    Wuhan, China
    Released mid
    April 2020

    HCQ 400mg / day
    62 patients in
    study; 31 HCQ,
    31 control group

    31 tx with
    HCQ

    25
    improved
    (vs. 17 in
    control
    group, p =
    0.0476

    0 deaths 25/31
    80.65%
    success
    rate

    Dr. Mehmet C.
    Oz
    New York, New
    York

    2 2 2 0 100%

    Dr. Mohammed
    A. Arsiwala,
    internist, in
    Livonia,
    Michigan

    Dr. Arswiwala
    says he has treated
    16 patients so far
    including Rep.
    Karen Whitsett in
    MI, data on others
    not available yet

    1 1 0 100%
    (N=1)

    6

    Mark Campbell,
    former Buffalo
    Bills football
    player, self
    report, physician
    name ?

    1 Treated with
    HCQ

    1 1 0 100%
    (N=1)

    Magagnoli J,
    Narendran S,
    Pereira F, et al.
    VA Health Care
    System,
    Columbia, South
    Carolina

    368 Veterans 210 with
    severe
    disease
    treated;
    Ventilation
    in 13.3% of
    HCQ group
    and 6.9%
    of
    HCQ+AZ
    group

    158 52 75.24%

    Dr. Idir Bitam
    Algeria
    4.26.20

    170 170 treated
    w/ HCQ +
    AZ

    165
    “returned
    to health”

    ? 97%

    Others

    7

    Conclusions as
    of 4.26.20
    See figures in
    bold

    Total patients
    seen by these
    physicians =
    3,868
    -------------------
    Which includes
    Dr. Zelenko’s new
    data as of 4.12.20
    2,065 + 654 =
    2,719 + 350 which
    includes new
    Raoult data from
    4.20.20
    3,069 + 211 from
    Lee Son and Peck
    3,280
    plus
    62+16+1+368 + 2
    (Oz) – 31
    (duplicate) + 170
    (Dr. Bitam) =
    3,868

    Total
    patients
    treated with
    HCQ, plus
    or minus
    azithromyci
    n and/or
    zinc = 2,333
    ------------
    1,533
    +205 Dr.
    Zelenko’s
    series
    update =
    1,738
    1,738 +
    211 =
    1,949
    +
    31+1+1+21
    0 -31
    duplicate
    +2 (Oz) +
    170
    (Bitam) =
    2,333

    Total
    patients
    clinically
    improved
    = 2,137
    ------------
    91.6 %
    treated with
    HCQ
    improved
    or never
    contracted
    CoVID-19
    despite
    being
    exposed
    2,137/2,33
    3 =
    91.6%

    Total
    deaths in
    those
    treated
    with
    HCQ or
    HCQ +
    AZ +/-
    zinc
    = 63
    63/ 2,333
    P(D) =
    2.7%

    Updated
    probabilit
    y of
    success in
    preventing
    death,
    P(D-),
    from
    CoVID-19
    using
    HCQ or
    HCQ +
    AZ = 91.6
    %

    This table is provisional and is being updated as new data surface.
    Please note that the Veteran’s Administration study conducted by Magagnoli J,
    Narendran S, Pereira F, et al. in South Carolina assessed a very sick population and the
    hydroxychloroquine was given late the course of the illness. Many patients were
    ventilated. We believe the 52 deaths reported in this population are not indicative or
    predictive of the average death rate observed in populations diagnosed in the early to mid
    stage of the CoVID-19 disease and treated with hydroxychloroquine. Based on the
    experienced clinicians observational data summarized above, the death count was only 11
    out of over 2,000 patients treated with hydroxychloroquine.
    Dr. Stephen Smith’s patients who were treated with HCQ and azithromycin did not
    require mechanical ventilation. He reports that severely ill CoVID-19 patients under 70
    yrs of age were diabetic or prediabetic with high BMI. He is convinced

    8
    hydroxychloroquine works for his patients. His level of certainty is very high. –
    personally reported on 4.2.20 and again on subsequent dates in April 2020.
    Clinicians are natural Bayesians and such philosophical and qualitative statistical analysis
    is consistent with our medical training, bedside clinical skills including history taking,
    examination, differential diagnosis, probable primary diagnosis, laboratory evaluations
    including serologies, EKG, chest X-ray, CT scan of lungs, objective gold standard test
    interpretation and clinical decision making. In other words, waiting for fixed randomized
    controlled trials during a pandemic when time is of the essence, a Bayesian approach to
    the assessment of diagnostic and therapeutic probabilities is wise and efficient and will
    save time, money and lives if the physicians are given a chance to retain their autonomy
    and practice medicine to the best of their abilities.
    Special thanks to Jeremy Snavely and Marilyn Singleton at AAPS and Avery Knapp,
    M.D. at the KnappGroup for assisting in the gathering of clinical information, research,
    and other data.
    Special thanks to the Bayesian statisticians at Arizona State University, University of
    Arizona BIO5 and the International Society for Bayesian Analysis for their valuable input
    and direction and ongoing assistance.
    Disclaimer: these results are preliminary and provisional because observational data from
    experienced clinicians are dynamic and may or may not be incomplete or of insufficient
    granularity to make more specific associations and interpretations. Moreover, some of the
    papers are undergoing the peer-review process, but have been shared with the world to
    reduce delays in clinical decision making. Likelihood ratios and Bayes’ factors cannot be
    computed yet since fixed randomized controlled trials (RCTs) are just starting around the
    world.
    A flat prior (0.5 probability where 0 is impossible and 1 is certain) could be used to
    represent one’s beliefs about whether hydroxychloroquine (HCQ) would result in clinical
    improvement and/or prevention of death from CoVID-19 based on knowledge up to
    December 2019 and January 2020. Based on the new observational studies and reports
    from several (more than 10) different medical sources in February, March and April
    2020, the prior will be updated using Bayes theorem yielding a posterior probability
    density when sufficient data to calculate likelihood ratios emerge. At present, physicians
    have a significant amount of basic science and human observational data to incorporate
    into their baseline knowledge of hydroxychloroquine safety and efficacy plus the current
    info included in this table will facilitate the physician as beliefs are updated accordingly.
    Based on the current clinical information available, the success rates for a favorable
    outcome/clinical improvement are approximately 91.6% using hydroxychloroquine
    (HCQ) without or without azithromycin (AZ) and/or zinc and the death rate in this treated
    group is approximately 2.7%.

    9
    In comparison, the probability of death is 0.5-0.85 or 50 to 85% when patients with
    CoVID-19 are on mechanical ventilation and the probability of death based on Johns
    Hopkins University data worldwide is 206,544/2,971,477 or 6.95% as of 4.26.20.
    At this time, the data from 9 observational reports and one controlled trial suggest that
    hydroxychloroquine is dramatically more effective at preventing death from CoVID-19
    than mechanical ventilation. It is encouraging to note that ventilated patients treated with
    hydroxychloroquine have been able to undergo successful extubation and transfer out of
    the intensive care unit onto the floor. Moreover, CoVID-19 viral loads have been reduced
    to low or undetectable levels after 5-15 days of treatment with hydroxychloroquine.
    The NIH initiated a study today to investigate hydroxychloroquine for prophylactic and
    active treatment for the novel betacoronavirus, CoVID-19.
    Numerous CoVID-19 studies utlizing hydroxychloroquine for either prophylaxis or
    treatment are listed on the clinicaltrials.gov site but many of them have not started
    enrolling patients yet.
    One trial out of Washington University in St. Louis, MO is a Bayesian adaptive design
    trial using hydroxychloroquine as a prophylactic drug against CoVID-19.
    The table shows several international studies that are underway reportedly but this list is
    provisional and no data is available yet from these centers conducting randomized
    controlled trials.
    As new data surface, we will be able to update the table and make additional Bayesian
    inferences that may assist physicians in clinical decision making.
    As Ben Carson, MD, pediatric neurosurgeon and HUD Secretary, has recently reminded
    us, physicians treating suspected or confirmed CoVID-19 patients should ask themselves
    during this pandemic:
    What is the best clinical outcome that can happen if I use hydroxycholorquine?
    What is the worst clinical outcome that can happen if I use hydroxychloroquine?
    What is the best clinical outcome that can happen if I do not use hydroxychloroquine?
    What is the worst clinical outcome that can happen if I do not use hydroxychloroquine?
    This table is a continuous work in progress.

    10
    Comments or additional contributions to the data set may be forwarded to the Association
    of American Physicians and Surgeons (AAPS) in Tucson, AZ, established 1943,
    dedicated to preserving the patient-doctor relationship and liberty in medicine, see
    www.aapsonline.org for more information.
    Sincerely,
    /Michael J. A. Robb, M.D./
    Michael J. A. Robb, M.D.
    Physician
    Practice of Private Oto-Neurology
    Past President, Association of American Physicians and Surgeons (AAPS)
    Board of Director, AAPS
    Arizona State Chapter President, AAPS

    source >> https://drive.google.com/file/d/1w6p_HqRXCrW0_wYNK7m_zpQLbBVYcvVU/view
  13. The AAPS that composed that table is a conservative group that also claim:

    HIV doesn't lead to AIDS

    Being gay reduces your life expectancy

    Abortion causes breast cancer

    Vaccines cause autism

    The government should not be running anti-smoking/nicotine addiction campaigns

    Global warming is actually a good thing, but it's not caused by humans


    You've posted links from them before and I brought this up last time too. They aren't credible. It's supposed to be a group of doctors but they have an official stance on gun control.

    Yeah Speccy, real good source there.
  14. -SpectraL coward [the spuriously bluish-lilac bushman]
    Originally posted by MexicanMasterRace The AAPS that composed that table is a conservative group that also claim:

    HIV doesn't lead to AIDS

    Being gay reduces your life expectancy

    Abortion causes breast cancer

    Vaccines cause autism

    The government should not be running anti-smoking/nicotine addiction campaigns

    Global warming is actually a good thing, but it's not caused by humans


    You've posted links from them before and I brought this up last time too. They aren't credible. It's supposed to be a group of doctors but they have an official stance on gun control.

    Yeah Speccy, real good source there.

    The numbers are valid. Again, you are just attacking the messenger, rather than acknowledging the accuracy and significance of the content. You are what I call a professional denier. A Denialist, if you will. No amount of evidence or proof would ever satisfy your hyper-partisan, predetermined stance on anything that doesn't fit your script.
  15. Originally posted by -SpectraL The numbers are valid. Again, you are just attacking the messenger, rather than acknowledging the accuracy and significance of the content. You are what I call a professional denier. A Denialist, if you will. No amount of evidence or proof would ever satisfy your hyper-partisan, predetermine stance on anything.

    I would need a link to the individual studies. There are studies on all kinds of things. It doesn't make it true.

    What is objectively true are the deaths due to this drug that Fox News said it is a "cure for coronavirus" and Trump said, "Try it, what harm can it do?" Few days later that couple died.

    Don't see any other drugs they're using killing people.
  16. Also you don't even think the coronavirus is real so how can it be effective against curing it??
  17. -SpectraL coward [the spuriously bluish-lilac bushman]
    Originally posted by MexicanMasterRace I would need a link to the individual studies. There are studies on all kinds of things. It doesn't make it true.

    What is objectively true are the deaths due to this drug that Fox News said it is a "cure for coronavirus" and Trump said, "Try it, what harm can it do?" Few days later that couple died.

    Don't see any other drugs they're using killing people.

    They ate fishbowl cleaner, dummy.
  18. -SpectraL coward [the spuriously bluish-lilac bushman]
    Originally posted by MexicanMasterRace Also you don't even think the coronavirus is real so how can it be effective against curing it??

    I never said it's not real. In fact, I said the exact opposite - that it IS real. The globalist hoax is that it's some killer virus going to kill millions. The coronavirus is not much more severe than the common flu. The scam is to terrorize the nations, and then bring in their New World Order on the back of that terror, using the coronavirus as the smokescreen.
  19. Technologist victim of incest
    Originally posted by MexicanMasterRace I would need a link to the individual studies. There are studies on all kinds of things. It doesn't make it true.

    What is objectively true are the deaths due to this drug that Fox News said it is a "cure for coronavirus" and Trump said, "Try it, what harm can it do?" Few days later that couple died.

    Don't see any other drugs they're using killing people.

    I’d hedge a bet that some people are going to die from taking hydroxychloriquine now that trump says he’s taking it.
  20. Oh, okay then.
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