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Make morphine with yeast!
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2015-07-28 at 7:03 AM UTCDo it up niggers. This should get you on the right track:
http://europepmc.org/articles/pmc4167936 -
2015-07-28 at 5:19 PM UTCI don't know shit about bio chemistry or isolating enzymes. I'm just gonna get rich and pay some lab in India to do it for me.
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2015-07-28 at 6:18 PM UTC[SIZE=12px] Because of the complex regioand stereochemistry of morphinan BIAs, chemical synthesis of these molecules is not viable at commercial scale5. Currently, the world relies on opium poppy trade to meet the medical demand for opiates and their derivatives.[/SIZE]
[SIZE=12px]Knowledge of the opiate biosynthetic pathway informs modern crop breeding and metabolic engineering efforts to improve opium poppy as a plant production host. This understanding increased greatly with the recent discovery of the remaining enzymatic steps in morphine biosynthesis6, in which the reactions converting thebaine to morphine are catalyzed by codeinone reductase (COR) and the newly-identified dioxygenases thebaine 6-O-demethylase (T6ODM) and codeine O-demethylase (CODM). Overexpression of COR confers enhanced overall morphinan alkaloid content7, and knockdown of individual pathway genes results in accumulation of morphinan [/SIZE]
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2017-02-18 at 9:53 AM UTCvaguely familiar ...heard of something like this
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2017-06-06 at 4:26 AM UTCAlways think about thea availability of plants
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2017-06-11 at 1:43 AM UTCThe yeast needs to be engineered first apparently.
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2017-06-11 at 3:29 AM UTCJust make it all synthetic starting from this route
https://en.m.wikipedia.org/wiki/Petrenko-Kritschenko_piperidone_synthesis
